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Generated: December 17, 2018

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CLINICAL TRIALS PROFILE FOR ATACAND HCT

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Clinical Trials for Atacand Hct

Trial ID Title Status Sponsor Phase Summary
NCT00150631 Danish Hypertension Prevention Project - DHYPP Unknown status AstraZeneca Phase 3 The present study examine healthy, normotensive subjects 18 to 36 years of age whose both parents have essential hypertension. The subjects receive treatment with either the AT1-antagonist candesartan cilexetil, 16 mg daily or placebo for one year. Then, treatment is withdrawn and the subjects is followed for 10 years to determine if the treatment has been able to either prevent or delay the development of hypertension. The primary objective is to determine whether pharmacological treatment with an angiotensin receptor blocker is able to restrain or delay the progression to hypertension. Secondary objectives are to investigate whether any long-term effect on blood pressure is related to the effect of treatment on renal haemodynamic function, or on the left ventricle mass.
NCT00150631 Danish Hypertension Prevention Project - DHYPP Unknown status University of Aarhus Phase 3 The present study examine healthy, normotensive subjects 18 to 36 years of age whose both parents have essential hypertension. The subjects receive treatment with either the AT1-antagonist candesartan cilexetil, 16 mg daily or placebo for one year. Then, treatment is withdrawn and the subjects is followed for 10 years to determine if the treatment has been able to either prevent or delay the development of hypertension. The primary objective is to determine whether pharmacological treatment with an angiotensin receptor blocker is able to restrain or delay the progression to hypertension. Secondary objectives are to investigate whether any long-term effect on blood pressure is related to the effect of treatment on renal haemodynamic function, or on the left ventricle mass.
NCT00150631 Danish Hypertension Prevention Project - DHYPP Unknown status Karin Skov Phase 3 The present study examine healthy, normotensive subjects 18 to 36 years of age whose both parents have essential hypertension. The subjects receive treatment with either the AT1-antagonist candesartan cilexetil, 16 mg daily or placebo for one year. Then, treatment is withdrawn and the subjects is followed for 10 years to determine if the treatment has been able to either prevent or delay the development of hypertension. The primary objective is to determine whether pharmacological treatment with an angiotensin receptor blocker is able to restrain or delay the progression to hypertension. Secondary objectives are to investigate whether any long-term effect on blood pressure is related to the effect of treatment on renal haemodynamic function, or on the left ventricle mass.
NCT00242346 High Doses of Candesartan Cilexetil on the Reduction of Proteinuria Completed AstraZeneca Phase 3 The purpose of this study is to assess the effects of high doses of candesartan cilexetil and also to assess which dose (16mg, 64mg, 128mg) is the most optimal for the maximum reduction of proteinuria.
NCT00244621 Atacand Dose Ranging in Hypertensive Pediatric Subjects 1 Year to Less Than 6 Years of Age Completed AstraZeneca Phase 3 This is a dose ranging study of candesartan cilexetil in hypertensive pediatric subjects ages 1 to less than 6 years of age. It employs a double blind, randomized, dose ranging design intended for conduct as a multicenter trial. There are 3 study 'periods': a 1-week placebo run-in, a 4-week double blind treatment, and a 52-week open-label, long-term treatment period. Subjects undergo a screening evaluation, then a 1-week single-blind, placebo run-in, after which eligible subjects are allocated to receive 1 of 3 dose levels of candesartan cilexetil (0.05 mg/kg, or 0.20 mg /kg or 0.40 mg /kg), liquid formulation, in a 1:1:1 ratio for 4-weeks. At the end of randomized dose allocation (Day 28), blood pressure assessment will be performed and subjects may begin the 52-week, open-label treatment period of the study.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Atacand Hct

Condition Name

Condition Name for Atacand Hct
Intervention Trials
Hypertension 14
Congestive Heart Failure 4
Heart Failure 3
Aortic Valve Stenosis 2
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Condition MeSH

Condition MeSH for Atacand Hct
Intervention Trials
Hypertension 8
Heart Failure 7
Cognition Disorders 3
Proteinuria 2
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Clinical Trial Locations for Atacand Hct

Trials by Country

Trials by Country for Atacand Hct
Location Trials
United States 42
France 39
Korea, Republic of 16
Canada 8
Denmark 4
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Trials by US State

Trials by US State for Atacand Hct
Location Trials
California 4
Texas 4
Georgia 3
Pennsylvania 2
North Carolina 2
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Clinical Trial Progress for Atacand Hct

Clinical Trial Phase

Clinical Trial Phase for Atacand Hct
Clinical Trial Phase Trials
Phase 4 9
Phase 3 14
Phase 2 5
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Clinical Trial Status

Clinical Trial Status for Atacand Hct
Clinical Trial Phase Trials
Completed 24
Recruiting 4
Unknown status 4
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Clinical Trial Sponsors for Atacand Hct

Sponsor Name

Sponsor Name for Atacand Hct
Sponsor Trials
AstraZeneca 18
Takeda 4
GlaxoSmithKline 4
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Sponsor Type

Sponsor Type for Atacand Hct
Sponsor Trials
Industry 28
Other 25
NIH 5
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