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Last Updated: October 16, 2019

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CLINICAL TRIALS PROFILE FOR ARSENIC TRIOXIDE

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Clinical Trials for Arsenic Trioxide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003395 Arsenic Trioxide in Treating Patients With Advanced Hematologic Cancer Completed National Cancer Institute (NCI) Phase 1 1998-04-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced hematologic cancer.
NCT00003395 Arsenic Trioxide in Treating Patients With Advanced Hematologic Cancer Completed Memorial Sloan Kettering Cancer Center Phase 1 1998-04-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced hematologic cancer.
NCT00003630 Arsenic Trioxide in Treating Patients With Advanced Solid Tumors Completed National Cancer Institute (NCI) Phase 1 1998-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced solid tumors.
NCT00003630 Arsenic Trioxide in Treating Patients With Advanced Solid Tumors Completed Memorial Sloan Kettering Cancer Center Phase 1 1998-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced solid tumors.
NCT00003885 Arsenic Trioxide in Treating Patients With Recurrent or Refractory Acute Leukemia, Chronic Myeloide Leukemia, Myelodysplasia, Lymphoma, or Myeloma Unknown status Our Lady of Mercy Medical Center Phase 2 1997-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of arsenic trioxide in treating patients who have recurrent or refractory acute leukemia, chronic myeloid leukemia, myelodysplasia, lymphoma, or myeloma.
NCT00003934 Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia Completed National Cancer Institute (NCI) Phase 3 1999-06-01 This randomized phase III trial is studying tretinoin and combination chemotherapy to see how well they work compared to tretinoin, combination chemotherapy, and arsenic trioxide in treating patients with acute promyelocytic leukemia that has not been treated previously. Drugs used in chemotherapy, such as daunorubicin, cytarabine, mercaptopurine, methotrexate, and arsenic trioxide, work in different ways to stop cancer cells from dividing so they stop growing or die. Tretinoin may help leukemia cells develop into normal white blood cells. It is not yet known which regimen is more effective for acute promyelocytic leukemia.
NCT00004149 Arsenic Trioxide in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Previous Hormone Therapy Completed National Cancer Institute (NCI) Phase 2 1999-09-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of arsenic trioxide in treating patients who have stage IV prostate cancer that has not responded to hormone therapy.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Arsenic Trioxide

Condition Name

Condition Name for Arsenic Trioxide
Intervention Trials
Leukemia 31
Acute Promyelocytic Leukemia 12
Myelodysplastic Syndromes 11
Multiple Myeloma and Plasma Cell Neoplasm 9
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Condition MeSH

Condition MeSH for Arsenic Trioxide
Intervention Trials
Leukemia 58
Leukemia, Promyelocytic, Acute 27
Leukemia, Myeloid 20
Neoplasms, Plasma Cell 17
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Clinical Trial Locations for Arsenic Trioxide

Trials by Country

Trials by Country for Arsenic Trioxide
Location Trials
United States 308
China 19
Spain 9
Canada 9
India 6
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Trials by US State

Trials by US State for Arsenic Trioxide
Location Trials
New York 27
California 23
Texas 18
Illinois 17
Florida 13
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Clinical Trial Progress for Arsenic Trioxide

Clinical Trial Phase

Clinical Trial Phase for Arsenic Trioxide
Clinical Trial Phase Trials
Phase 4 4
Phase 3 9
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Arsenic Trioxide
Clinical Trial Phase Trials
Completed 53
Terminated 20
Recruiting 18
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Clinical Trial Sponsors for Arsenic Trioxide

Sponsor Name

Sponsor Name for Arsenic Trioxide
Sponsor Trials
National Cancer Institute (NCI) 50
Cephalon 12
Memorial Sloan Kettering Cancer Center 11
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Sponsor Type

Sponsor Type for Arsenic Trioxide
Sponsor Trials
Other 130
NIH 52
Industry 36
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