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Generated: December 12, 2018

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CLINICAL TRIALS PROFILE FOR ARIDOL KIT

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Clinical Trials for Aridol Kit

Trial ID Title Status Sponsor Phase Summary
NCT00117182 Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD Completed Pharmaxis Phase 2 The purpose of this study is to determine whether the Aridol (mannitol) challenge test can predict response to treatment with inhaled corticosteroids in COPD subjects. Subjects will undergo an Aridol test and then 3 months of treatment with inhaled corticosteroids. The effect on lung function and quality of life will then be measured and correlated with the Aridol test result.
NCT00252291 Ability of Aridol to Detect Bronchial Hyperresponsiveness in Suspected Asthmatics Completed Pharmaxis Phase 3 This is a Phase 3 study to determine the sensitivity and specificity of the Aridol bronchial challenge test to detect bronchial hyperresponsiveness in patients with suspected asthma. Patients with suspected asthma of either gender, aged between 6 and 50 years, with only mildly impaired lung function (FEV1 >70%) are to be tested with three different bronchial hyperresponsiveness challenges (Aridol, exercise and methacholine), and the results compared. A clinical diagnosis will also be made at the end of the study.
NCT01064245 Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge Tests Active, not recruiting Queen's University (William M Spear / Start Memorial Fund) N/A Cough is a common, disruptive and at times disabling symptom which often prompts patients to seek medical attention. Determining the cause(s) of chronic cough can be challenging, and costly. Asthma and other airway disorders are among the most common causes of chronic cough; and cough can be the sole symptom of asthma. Little is known about why some patients with asthma primarily cough and do not develop the other symptoms of asthma such as shortness of breath or wheeze. Improved understanding of the reasons for these different manifestations may lead to new and more effective treatment strategies. We have notices differences in pressure measurements inside the chest in patients who mostly cough during induced bronchoconstriction, which might be part of the explanation for varying symptoms. This study will compare lung mechanical responses during methacholine and mannitol-induced induced airway narrowing between typical asthma, cough variant asthma (CVA) and an airway inflammatory disorder that is not asthma.The purpose of this research is to explore the pathophysiology and sensory-mechanics of cough in individuals with asthma, CVA and methacholine-induced cough but normal airway sensitivity using mannitol and high-dose methacholine bronchoprovocation testing.
NCT01064245 Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge Tests Active, not recruiting The Ontario Thoracic Society of the Ontario Lung Association N/A Cough is a common, disruptive and at times disabling symptom which often prompts patients to seek medical attention. Determining the cause(s) of chronic cough can be challenging, and costly. Asthma and other airway disorders are among the most common causes of chronic cough; and cough can be the sole symptom of asthma. Little is known about why some patients with asthma primarily cough and do not develop the other symptoms of asthma such as shortness of breath or wheeze. Improved understanding of the reasons for these different manifestations may lead to new and more effective treatment strategies. We have notices differences in pressure measurements inside the chest in patients who mostly cough during induced bronchoconstriction, which might be part of the explanation for varying symptoms. This study will compare lung mechanical responses during methacholine and mannitol-induced induced airway narrowing between typical asthma, cough variant asthma (CVA) and an airway inflammatory disorder that is not asthma.The purpose of this research is to explore the pathophysiology and sensory-mechanics of cough in individuals with asthma, CVA and methacholine-induced cough but normal airway sensitivity using mannitol and high-dose methacholine bronchoprovocation testing.
NCT01064245 Physiology of Cough in Asthma: Comparison of Sensory-Mechanical Responses to Mannitol and Methacholine Challenge Tests Active, not recruiting Queen's University N/A Cough is a common, disruptive and at times disabling symptom which often prompts patients to seek medical attention. Determining the cause(s) of chronic cough can be challenging, and costly. Asthma and other airway disorders are among the most common causes of chronic cough; and cough can be the sole symptom of asthma. Little is known about why some patients with asthma primarily cough and do not develop the other symptoms of asthma such as shortness of breath or wheeze. Improved understanding of the reasons for these different manifestations may lead to new and more effective treatment strategies. We have notices differences in pressure measurements inside the chest in patients who mostly cough during induced bronchoconstriction, which might be part of the explanation for varying symptoms. This study will compare lung mechanical responses during methacholine and mannitol-induced induced airway narrowing between typical asthma, cough variant asthma (CVA) and an airway inflammatory disorder that is not asthma.The purpose of this research is to explore the pathophysiology and sensory-mechanics of cough in individuals with asthma, CVA and methacholine-induced cough but normal airway sensitivity using mannitol and high-dose methacholine bronchoprovocation testing.
NCT01642745 Mannitol (Aridol) and Methacholine (Provocholine) Responsiveness Completed University of Saskatchewan Phase 4 The study will compare the airway responses to two bronchoconstricting agents, mannitol and methacholine.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Aridol Kit

Condition Name

Condition Name for Aridol Kit
Intervention Trials
Asthma 5
Lung Diseases, Obstructive 1
Cough Variant Asthma 1
Cough 1
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Condition MeSH

Condition MeSH for Aridol Kit
Intervention Trials
Asthma 3
Cough 2
Respiratory Aspiration 1
Bronchial Hyperreactivity 1
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Clinical Trial Locations for Aridol Kit

Trials by Country

Trials by Country for Aridol Kit
Location Trials
Canada 5
Australia 5
United States 1
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Trials by US State

Trials by US State for Aridol Kit
Location Trials
Colorado 1
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Clinical Trial Progress for Aridol Kit

Clinical Trial Phase

Clinical Trial Phase for Aridol Kit
Clinical Trial Phase Trials
Phase 4 1
Phase 3 2
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Aridol Kit
Clinical Trial Phase Trials
Completed 4
Not yet recruiting 1
Recruiting 1
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Clinical Trial Sponsors for Aridol Kit

Sponsor Name

Sponsor Name for Aridol Kit
Sponsor Trials
University of Saskatchewan 3
Pharmaxis 3
AllerGen NCE Inc. 1
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Sponsor Type

Sponsor Type for Aridol Kit
Sponsor Trials
Other 7
Industry 4
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Serving hundreds of leading biopharmaceutical companies globally:

Cipla
Moodys
Chinese Patent Office
Express Scripts
US Department of Justice
AstraZeneca
Covington
US Army
Argus Health

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