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CLINICAL TRIALS PROFILE FOR AMILORIDE HYDROCHLORIDE

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Clinical Trials for Amiloride Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00004705	Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis	Completed	University of North Carolina	N/A	OBJECTIVES: I. Determine the stability of uridine triphosphate (UTP) and examine the metabolism of exogenous nucleotides on airway epithelial surfaces in patients with cystic fibrosis. II. Determine the acute safety and efficacy of aerosolized UTP in children with cystic fibrosis.
NCT00004705	Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis	Completed	FDA Office of Orphan Products Development	N/A	OBJECTIVES: I. Determine the stability of uridine triphosphate (UTP) and examine the metabolism of exogenous nucleotides on airway epithelial surfaces in patients with cystic fibrosis. II. Determine the acute safety and efficacy of aerosolized UTP in children with cystic fibrosis.
NCT00007592	Hypertension Screening and Treatment Program	Completed	VA Office of Research and Development	N/A	Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00141596	Extracellular Fluid in Resistant Hypertension	Terminated	St George's, University of London	N/A	The optimal treatment of drug resistant (defined as BP> 140/85 despite three anti-hypertensive drugs including a diuretic) is not well defined. This study aims to test the hypothesis that resistant hypertension is caused by excessive expansion of extracellular fluid volume. A secondary objective is to study which of three different antihypertensive drugs would be most useful in drug resistant hypertension.

Clinical Trial Conditions for Amiloride Hydrochloride

Condition Name

Condition Name for Amiloride Hydrochloride
Intervention	Trials
Hypertension	17
Cystic Fibrosis	7
Proteinuria	2
Chronic Kidney Disease	2

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Condition MeSH

Condition MeSH for Amiloride Hydrochloride
Intervention	Trials
Hypertension	19
Fibrosis	7
Cystic Fibrosis	7
Kidney Diseases	4

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Clinical Trial Locations for Amiloride Hydrochloride

Trials by Country

Trials by Country for Amiloride Hydrochloride
Location	Trials
United States	28
Brazil	13
France	7
United Kingdom	7
Denmark	5

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Trials by US State

Trials by US State for Amiloride Hydrochloride
Location	Trials
North Carolina	3
Pennsylvania	3
Maryland	2
Massachusetts	2
Tennessee	2

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Clinical Trial Progress for Amiloride Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Amiloride Hydrochloride
Clinical Trial Phase	Trials
Phase 4	14
Phase 3	7
Phase 2/Phase 3	5

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Clinical Trial Status

Clinical Trial Status for Amiloride Hydrochloride
Clinical Trial Phase	Trials
Completed	23
Recruiting	12
Not yet recruiting	6

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Clinical Trial Sponsors for Amiloride Hydrochloride

Sponsor Name

Sponsor Name for Amiloride Hydrochloride
Sponsor	Trials
Hospital de Clinicas de Porto Alegre	5
Assistance Publique - Hôpitaux de Paris	5
Cystic Fibrosis Foundation Therapeutics	3

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Sponsor Type

Sponsor Type for Amiloride Hydrochloride
Sponsor	Trials
Other	94
Industry	6
U.S. Fed	3

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