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Last Updated: October 15, 2019

DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR AMANTADINE HYDROCHLORIDE

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Clinical Trials for Amantadine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000301 Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4 Completed National Institute on Drug Abuse (NIDA) Phase 2 1996-03-01 The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested."
NCT00000301 Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4 Completed University of California, Los Angeles Phase 2 1996-03-01 The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested."
NCT00001930 Treatment of Huntington's Chorea With Amantadine Completed National Institute of Neurological Disorders and Stroke (NINDS) Phase 2 1999-04-01 Huntington's disease is a chronic disorder passed on through genetic autosomal dominant inheritance. The condition usually begins between the ages of 30 and 50 years and it is characterized by involuntary movements in the face and extremities, (chorea), accompanied by changes in behavior and gradual loss of the mental function. The disease typically ends in a state of disorientation, impaired memory, judgement, and intellect (dementia). The objective of this study is to test the effectiveness of the drug amantadine for the treatment of chorea associated with Huntington's disease. Amantadine is an antiviral drug that has been used to treat a variety of illnesses including Parkinson's disease. Amantadine works by attaching to special sites called NMDA (N-methyl-D-aspartate) receptors and blocking the normal activity of glutamate there. Glutamate is an amino acid released by brain cells and has been associated with the symptoms of Parkinson's disease.
NCT00015249 Prepulse Inhibition of Startle in Cocaine Dependence - 7 Completed New York MDRU Phase 1 1997-02-01 The purpose of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.
NCT00015249 Prepulse Inhibition of Startle in Cocaine Dependence - 7 Completed National Institute on Drug Abuse (NIDA) Phase 1 1997-02-01 The purpose of this study is to assess the effects of chronic cocaine use on the acoustic startle response and on gating of this response in humans.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Amantadine Hydrochloride

Condition Name

Condition Name for Amantadine Hydrochloride
Intervention Trials
Parkinson's Disease 14
Traumatic Brain Injury 7
Parkinson Disease 7
Multiple Sclerosis 6
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Condition MeSH

Condition MeSH for Amantadine Hydrochloride
Intervention Trials
Parkinson Disease 27
Dyskinesias 13
Sclerosis 10
Multiple Sclerosis 10
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Clinical Trial Locations for Amantadine Hydrochloride

Trials by Country

Trials by Country for Amantadine Hydrochloride
Location Trials
United States 295
Germany 40
Canada 20
France 19
Spain 9
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Trials by US State

Trials by US State for Amantadine Hydrochloride
Location Trials
California 17
North Carolina 16
Texas 16
Florida 16
New York 15
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Clinical Trial Progress for Amantadine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Amantadine Hydrochloride
Clinical Trial Phase Trials
Phase 4 17
Phase 3 20
Phase 2/Phase 3 6
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Clinical Trial Status

Clinical Trial Status for Amantadine Hydrochloride
Clinical Trial Phase Trials
Completed 39
Recruiting 16
Terminated 12
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Clinical Trial Sponsors for Amantadine Hydrochloride

Sponsor Name

Sponsor Name for Amantadine Hydrochloride
Sponsor Trials
Adamas Pharmaceuticals, Inc. 8
Hoffmann-La Roche 5
Oregon Health and Science University 4
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Sponsor Type

Sponsor Type for Amantadine Hydrochloride
Sponsor Trials
Other 94
Industry 30
NIH 9
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