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Last Updated: January 18, 2020

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CLINICAL TRIALS PROFILE FOR ADRENALIN

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All Clinical Trials for Adrenalin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00202358 Perioperative Effect of Atenolol on Cytokine Profiles Unknown status Medtronic - MITG Phase 4 2002-11-01 Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seemed to improve outcomes up to 2 years later. This is hard to explain since beta-blockers act on the body by blocking the effects of adrenalin and thereby lowering heart rate and blood pressure. This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.
NCT00202358 Perioperative Effect of Atenolol on Cytokine Profiles Unknown status Saini Foundation Phase 4 2002-11-01 Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seemed to improve outcomes up to 2 years later. This is hard to explain since beta-blockers act on the body by blocking the effects of adrenalin and thereby lowering heart rate and blood pressure. This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.
NCT00562627 Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty Completed Asker & Baerum Hospital Phase 4 2007-11-01 Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee arthroplasty. 2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural analgesia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Adrenalin

Condition Name

Condition Name for Adrenalin
Intervention Trials
Pain 3
Bronchiolitis 2
Cataract 2
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Condition MeSH

Condition MeSH for Adrenalin
Intervention Trials
Pain, Postoperative 3
Bronchiolitis 2
Cataract 2
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Clinical Trial Locations for Adrenalin

Trials by Country

Trials by Country for Adrenalin
Location Trials
United States 7
France 4
Denmark 2
Norway 2
Italy 1
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Trials by US State

Trials by US State for Adrenalin
Location Trials
Massachusetts 2
New Hampshire 1
Georgia 1
Connecticut 1
Arizona 1
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Clinical Trial Progress for Adrenalin

Clinical Trial Phase

Clinical Trial Phase for Adrenalin
Clinical Trial Phase Trials
Phase 4 13
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Adrenalin
Clinical Trial Phase Trials
Completed 16
Not yet recruiting 7
Unknown status 4
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Clinical Trial Sponsors for Adrenalin

Sponsor Name

Sponsor Name for Adrenalin
Sponsor Trials
Seattle Institute for Biomedical and Clinical Research 1
Medtronic - MITG 1
Centre hospitalier de l'Université de Montréal (CHUM) 1
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Sponsor Type

Sponsor Type for Adrenalin
Sponsor Trials
Other 38
U.S. Fed 2
Industry 1
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