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Generated: January 21, 2019

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CLINICAL TRIALS PROFILE FOR ADRENALIN

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Clinical Trials for Adrenalin

Trial ID Title Status Sponsor Phase Summary
NCT00202358 Perioperative Effect of Atenolol on Cytokine Profiles Unknown status Medtronic - MITG Phase 4 Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seemed to improve outcomes up to 2 years later. This is hard to explain since beta-blockers act on the body by blocking the effects of adrenalin and thereby lowering heart rate and blood pressure. This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.
NCT00202358 Perioperative Effect of Atenolol on Cytokine Profiles Unknown status Saini Foundation Phase 4 Studies have shown that beta-blockers such as atenolol when given in the perioperative period reduce morbidity and mortality. One study showed that atenolol given just during the surgery period, seemed to improve outcomes up to 2 years later. This is hard to explain since beta-blockers act on the body by blocking the effects of adrenalin and thereby lowering heart rate and blood pressure. This study is designed to find out if perioperative atenolol might exert its long term effects through an anti-inflammatory mechanism rather than by lowering heart rate and blood pressure. It is known that inflammation increases after surgery as part of the healing process. However, it is also becoming clear that low-grade chronic inflammation can also lead to long term adverse effects.
NCT00562627 Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty Completed Asker & Baerum Hospital Phase 4 Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain, causing patient discomfort, mobilisation and hospital discharge. The aim of this study is to: 1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee arthroplasty. 2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural analgesia.
NCT00622817 The Influence of Inhaled Adrenalin Versus Decongestant as a Local Nasal Treatment in Bronchiolitis Completed Schneider Children's Medical Center, Israel N/A This was a randomized, double blinded, controlled trial. The aim of the study was to compare xylometazoline HCL nasal drops to inhalation of epinephrine as a treatment for bronchiolitis. The study hypothesis is:xylometazoline HCL nasal drops treatment is good as epinephrine inhalation for treatment of bronchiolitis. Signed informed consent was obtained from a parent of each child. And the human ethics committee of our hospital approved the study according to the principles of the Declaration of Helsinki.(Approved - 2002) Patients: 65 infants who were admitted to Pediatric A- a general pediatric ward, in Schneider Children's Medical Center because of bronchiolitis during winter in two consecutive years 2004-2005. The inclusion criteria were: Full term previously healthy Infants, ages 1-12 months, after informed consent was signed with clinical presentation of mild to moderate bronchiolitis according to a clinical score .Exclusion criteria were as follows: prematurity, congenital lung or cardiac disease, infants who had past hospitalization due to respiratory illness and severe bronchiolitis (score>7 with a range scale 0-10).
NCT00685672 Safety of Epidural Fentanyl and Adrenalin During Childbirth Completed University Hospital, Akershus Phase 4 Investigation of pharmacokinetic effects of combining fentanyl and adrenalin in the epidural solution given to women in childbirth
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Adrenalin

Condition Name

Condition Name for Adrenalin
Intervention Trials
Pain 3
Surgery 2
Bronchiolitis 2
Maxillofacial Surgery 1
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Condition MeSH

Condition MeSH for Adrenalin
Intervention Trials
Pain, Postoperative 3
Bronchiolitis 2
Heart Diseases 1
Stress Disorders, Traumatic 1
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Clinical Trial Locations for Adrenalin

Trials by Country

Trials by Country for Adrenalin
Location Trials
United States 7
France 4
Denmark 2
Norway 2
Brazil 1
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Trials by US State

Trials by US State for Adrenalin
Location Trials
Massachusetts 2
Georgia 1
Connecticut 1
Arizona 1
Washington 1
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Clinical Trial Progress for Adrenalin

Clinical Trial Phase

Clinical Trial Phase for Adrenalin
Clinical Trial Phase Trials
Phase 4 13
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Adrenalin
Clinical Trial Phase Trials
Completed 16
Not yet recruiting 5
Unknown status 4
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Clinical Trial Sponsors for Adrenalin

Sponsor Name

Sponsor Name for Adrenalin
Sponsor Trials
Second University of Naples 1
University Hospital, Akershus 1
Kathmandu University School of Medical Sciences 1
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Sponsor Type

Sponsor Type for Adrenalin
Sponsor Trials
Other 35
U.S. Fed 2
Industry 1
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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Healthtrust
Julphar
Federal Trade Commission
Citi
Queensland Health
Chinese Patent Office
Merck
Fish and Richardson

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