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Generated: March 24, 2019

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CLINICAL TRIALS PROFILE FOR ACITRETIN

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Clinical Trials for Acitretin

Trial ID Title Status Sponsor Phase Summary
NCT00002143 Treatment of Psoriasis Using Acitretin in HIV-Positive Patients Completed Hoffmann-La Roche Phase 3 To determine the efficacy of acitretin in the treatment of psoriasis in HIV/AIDS patients. Etretinate, a retinoid, has proven successful in the treatment of HIV-infected patients with psoriasis, but it has an elimination half-life of 100 days. Acitretin, a metabolite of etretinate, has a much shorter half-life of 2 to 3 days. Acitretin has proven effective in treating psoriasis in patients without HIV infection by reducing skin involvement and clearing of the condition, but it has not been thoroughly evaluated in HIV-infected patients.
NCT00003611 Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation Completed National Cancer Institute (NCI) N/A RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of acitretin may be an effective way to prevent the recurrence or further development of skin cancer. PURPOSE: Randomized clinical trial to study the effectiveness of acitretin in preventing skin cancers in patients with at least two previously treated skin cancers who have undergone organ transplantation.
NCT00003611 Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation Completed Alliance for Clinical Trials in Oncology N/A RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of acitretin may be an effective way to prevent the recurrence or further development of skin cancer. PURPOSE: Randomized clinical trial to study the effectiveness of acitretin in preventing skin cancers in patients with at least two previously treated skin cancers who have undergone organ transplantation.
NCT00156247 Acitretin and Etanercept in Psoriasis Completed Connetics Corp. Phase 2 To determine whether acitretin plus etanercept is more effective than etanercept alone in clearing psoriasis plaques in adults.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Acitretin

Condition Name

Condition Name for Acitretin
Intervention Trials
Psoriasis 12
Non-melanomatous Skin Cancer 2
Psoriasis Vulgaris 2
HIV Infections 2
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Condition MeSH

Condition MeSH for Acitretin
Intervention Trials
Psoriasis 18
Skin Neoplasms 2
HIV Infections 2
Retinal Diseases 1
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Clinical Trial Locations for Acitretin

Trials by Country

Trials by Country for Acitretin
Location Trials
United States 14
Canada 7
Korea, Republic of 3
China 3
India 2
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Trials by US State

Trials by US State for Acitretin
Location Trials
Pennsylvania 3
Arizona 2
New York 2
South Dakota 1
North Dakota 1
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Clinical Trial Progress for Acitretin

Clinical Trial Phase

Clinical Trial Phase for Acitretin
Clinical Trial Phase Trials
Phase 4 9
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Acitretin
Clinical Trial Phase Trials
Completed 14
Unknown status 5
Active, not recruiting 2
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Clinical Trial Sponsors for Acitretin

Sponsor Name

Sponsor Name for Acitretin
Sponsor Trials
Postgraduate Institute of Medical Education and Research 3
Innovaderm Research Inc. 3
National Cancer Institute (NCI) 2
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Sponsor Type

Sponsor Type for Acitretin
Sponsor Trials
Other 34
Industry 8
NIH 2
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