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Last Updated: October 15, 2019

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CLINICAL TRIALS PROFILE FOR ACCUTANE

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Clinical Trials for Accutane

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003564 Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas Withdrawn National Cancer Institute (NCI) Phase 3 1969-12-31 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether giving procarbazine alone or with isotretinoin is more effective for recurrent primary malignant glioma. PURPOSE: Randomized phase III trial to compare the effectiveness of procarbazine alone or with isotretinoin in treating patients with recurrent primary malignant gliomas.
NCT00003564 Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas Withdrawn M.D. Anderson Cancer Center Phase 3 1969-12-31 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether giving procarbazine alone or with isotretinoin is more effective for recurrent primary malignant glioma. PURPOSE: Randomized phase III trial to compare the effectiveness of procarbazine alone or with isotretinoin in treating patients with recurrent primary malignant gliomas.
NCT00003599 Vitamin E in Preventing the Side Effects of Isotretinoin in Former and Current Smokers Who Are Receiving Isotretinoin to Prevent Lung Cancer Withdrawn National Cancer Institute (NCI) Phase 3 1969-12-31 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of isotretinoin may be an effective way to prevent lung cancer. Vitamin E may prevent the side effects of isotretinoin therapy. PURPOSE: Randomized clinical trial to study the effectiveness of vitamin E in preventing the side effects of isotretinoin in former and current smokers who are receiving isotretinoin to prevent lung cancer.
NCT00003599 Vitamin E in Preventing the Side Effects of Isotretinoin in Former and Current Smokers Who Are Receiving Isotretinoin to Prevent Lung Cancer Withdrawn M.D. Anderson Cancer Center Phase 3 1969-12-31 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of isotretinoin may be an effective way to prevent lung cancer. Vitamin E may prevent the side effects of isotretinoin therapy. PURPOSE: Randomized clinical trial to study the effectiveness of vitamin E in preventing the side effects of isotretinoin in former and current smokers who are receiving isotretinoin to prevent lung cancer.
NCT00004188 Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma Completed National Cancer Institute (NCI) Phase 3 2001-02-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: This randomized phase III trial is studying peripheral stem cell transplantation with treated peripheral stem cells following combination chemotherapy to see how well it works compared to peripheral stem cell transplantation with untreated peripheral stem cells following combination chemotherapy in treating patients with neuroblastoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Accutane

Condition Name

Condition Name for Accutane
Intervention Trials
Stage 4 Neuroblastoma 5
Recurrent Neuroblastoma 5
Stage 4S Neuroblastoma 4
Regional Neuroblastoma 4
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Condition MeSH

Condition MeSH for Accutane
Intervention Trials
Neuroblastoma 11
Central Nervous System Neoplasms 4
Nervous System Neoplasms 3
Glioma 2
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Clinical Trial Locations for Accutane

Trials by Country

Trials by Country for Accutane
Location Trials
United States 291
Canada 35
Australia 13
New Zealand 4
Puerto Rico 3
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Trials by US State

Trials by US State for Accutane
Location Trials
Texas 13
Pennsylvania 12
California 12
Ohio 11
Illinois 10
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Clinical Trial Progress for Accutane

Clinical Trial Phase

Clinical Trial Phase for Accutane
Clinical Trial Phase Trials
Phase 4 1
Phase 3 9
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Accutane
Clinical Trial Phase Trials
Completed 12
Active, not recruiting 5
Recruiting 3
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Clinical Trial Sponsors for Accutane

Sponsor Name

Sponsor Name for Accutane
Sponsor Trials
National Cancer Institute (NCI) 16
M.D. Anderson Cancer Center 6
Children's Oncology Group 5
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Sponsor Type

Sponsor Type for Accutane
Sponsor Trials
Other 19
NIH 17
Industry 6
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