Last Updated: September 24, 2026

CLINICAL TRIALS PROFILE FOR ALCAINE

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All Clinical Trials for ALCAINE

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT02951351 ↗	Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections	Completed	Research to Prevent Blindness	N/A	2016-10-12	The specific aims of this study are to compare patient experience with and without a proparacaine drop after povidone iodine.
NCT02951351 ↗	Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections	Completed	VitreoRetinal Surgery, PA	N/A	2016-10-12	The specific aims of this study are to compare patient experience with and without a proparacaine drop after povidone iodine.
NCT02951351 ↗	Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections	Completed	Mayo Clinic	N/A	2016-10-12	The specific aims of this study are to compare patient experience with and without a proparacaine drop after povidone iodine.
NCT02973581 ↗	SPI-directed Analgesia for Vitreoretinal Surgeries	Completed	Silesian University of Medicine	N/A	2016-02-01	The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively. Patients received general anaesthesia alone or combined with either preemptive analgesia using topical solution of 0,5% proxymetacaine or peribulbar block (0,5% bupivacaine with 2% lidokaine) or preemptive intravenous infusion of 1,0 g of metamizol or preemptive intravenous infusion of acetaminophen in a doseof 10-15mg/kg of body weight.
NCT02973581 ↗	SPI-directed Analgesia for Vitreoretinal Surgeries	Completed	Medical University of Silesia	N/A	2016-02-01	The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively. Patients received general anaesthesia alone or combined with either preemptive analgesia using topical solution of 0,5% proxymetacaine or peribulbar block (0,5% bupivacaine with 2% lidokaine) or preemptive intravenous infusion of 1,0 g of metamizol or preemptive intravenous infusion of acetaminophen in a doseof 10-15mg/kg of body weight.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for ALCAINE

Condition Name

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Condition Name for ALCAINE
Intervention	Trials
Dacryocystitis	2
Dacryostenosis	2
Epiphora	2
Postoperative Nausea and Vomiting	1
[disabled in preview]	1
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Condition MeSH

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Condition MeSH for ALCAINE
Intervention	Trials
Lacrimal Apparatus Diseases	2
Dacryocystitis	2
Myopia	1
Macular Edema	1
[disabled in preview]	1
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Clinical Trial Locations for ALCAINE

Trials by Country

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Trials by Country for ALCAINE
Location	Trials
United States	3
Taiwan	1
China	1
Poland	1
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Trials by US State

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Trials by US State for ALCAINE
Location	Trials
Louisiana	1
Michigan	1
Minnesota	1
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Clinical Trial Progress for ALCAINE

Clinical Trial Phase

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Clinical Trial Phase for ALCAINE
Clinical Trial Phase	Trials
Phase 4	3
N/A	2
Early Phase 1	1
[disabled in preview]	0
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Clinical Trial Status

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Clinical Trial Status for ALCAINE
Clinical Trial Phase	Trials
Recruiting	3
Completed	2
Unknown status	1
[disabled in preview]	0
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Clinical Trial Sponsors for ALCAINE

Sponsor Name

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Sponsor Name for ALCAINE
Sponsor	Trials
Louisiana State University Health Sciences Center in New Orleans	1
Buddhist Tzu Chi General Hospital	1
Research to Prevent Blindness	1
[disabled in preview]	2
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Sponsor Type

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Sponsor Type for ALCAINE
Sponsor	Trials
Other	10
[disabled in preview]	0
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