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Last Updated: April 26, 2024

Patent: 9,260,724

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Summary for Patent: 9,260,724

Title:	Optimization of expression of parvoviral rep and cap proteins in insect cells
Abstract:	The present invention relates to the improved production of recombinant parvoviral virions in insect cells. In particular, the invention relates to an improved process for the production of recombinant parvoviral virions in insect cells, wherein the full/empty parvoviral virion ratio is increased. The invention also relates to the production of parvoviral vectors that may be used in gene therapy and to improvements in expression of the viral Rep proteins that increase the productivity of parvoviral vectors.
Inventor(s):	Bakker; Andrew Christian (Almere, NL), Hermens; Wilhelmus Theodorus Johannes Maria Christiaan Maria Christ (Almere, NL), Noordman; Yvet (Utrecht, NL)
Assignee:	UNIQURE IP B.V. (Amsterdam, NL)
Application Number:	14/149,953
Patent Claims:	see list of patent claims

Details for Patent 9,260,724

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132	06/04/1986	⤷ Try a Trial	2028-02-19
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	For Injection	103132		⤷ Try a Trial	2028-02-19
Merck Sharp & Dohme Corp.	INTRON A	interferon alfa-2b	Injection	103132		⤷ Try a Trial	2028-02-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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