Last Updated: May 14, 2026

Patent: 8,080,414

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Summary for Patent: 8,080,414

Title:	Recombinant cell clones having increased stability and methods of making and using the same
Abstract:	Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
Inventor(s):	Manfred Reiter, Wolfgang Mundt, Friedrich Dorner
Assignee:	Baxalta GmbH, Baxalta Inc
Application Number:	US12/488,465
Patent Claims:	see list of patent claims

Details for Patent 8,080,414

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Novo Nordisk Inc.	NOVOEIGHT	antihemophilic factor (recombinant)	For Injection	125466	October 15, 2013	8,080,414	2029-06-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,080,414

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Country	Patent Number	Estimated Expiration
United States of America	RE46897	⤷ Start Trial
United States of America	RE46860	⤷ Start Trial
United States of America	RE46745	⤷ Start Trial
United States of America	8329465	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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