Patent: 6,916,787
✉ Email this page to a colleague
Summary for Patent: 6,916,787
| Title: | Method for producing hemin proteins using plant cells, resulting proteins and products containing same |
| Abstract: | A method for producing haemin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of an animal haemin protein capable of reversibly binding oxygen, or for a variant or portion of said protein component, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the haemin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying a haemin protein that includes a complex consisting of the protein or proteins coded for by said nucleic acid and at least one iron-containing porphyritic nucleus, or a plurality of such complexes. |
| Inventor(s): | Merot; Bertrand (Volvic, FR), Dieryck; Wilfrid (Saint-Pathus, FR), Lenee; Philippe (Noumea, FR), Marden; Michael (Aulnay-sous-Bois, FR), Gruber; Veronique (Chamalieres, FR), Pagnier; Renee-Josee (Le Kremlin-Bicetre, FR), Baudino; Sylvie (Orcines, FR), Poyart; Claude (Paris, FR) |
| Assignee: | Institut National de la Sante et de Recherche Medicale (Paris Cedex, FR) Meristern Therapeutics (Clermont-Ferrand, FR) |
| Application Number: | 10/085,853 |
| Patent Claims: | see list of patent claims |
Details for Patent 6,916,787
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Recordati Rare Diseases, Inc. | PANHEMATIN | hemin for injection | For Injection | 101246 | 07/20/1983 | ⤷ Try a Trial | 2015-07-17 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
