Patent: 5,001,151
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Summary for Patent: 5,001,151
| Title: | Aqueous nitroglycerin injection and manufacturing process |
| Abstract: | Nitroglycerin injection that is free of the customary organic solvents and has an extended shelf life of at least 1 year, consisting essentially of water, lactose, and nitroglycerin. Sodium chloride or dextrose may be added during manufacture or upon diluting with an infusion. Commercially safe manufacture and stable dispersion are assured by mixing lactose adsorbate, containing nitroglycerin, with water at high shear so that no nitroglycerin droplets coalesce. Stability is maintained by filtering and filling operations using nonreactive, nonleaching, nonadsorptive materials. |
| Inventor(s): | Alam; Abu s. (Libertyville), Joshi; Utpal G. (Hanover Park), Mehta; Jairaj U. (Forest Park), Sayeed; Fakrul A. A. (Mundelein), Kapoor; John N. (Lake Forest, IL) |
| Assignee: | Fujisawa USA, Inc. (Deerfield, IL) |
| Application Number: | 07/372,910 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,001,151
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Merck Sharp & Dohme Corp. | ZOSTAVAX | zoster vaccine live | For Injection | 125123 | 05/25/2006 | ⤷ Try a Trial | 2007-08-11 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
