Patent: 4,425,428
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Summary for Patent: 4,425,428
Title: | Novel peptide and peptolide substrates for mammalian collagenase |
Abstract: | Method for determination of the enzyme collagenase by reacting the enzyme with a peptide or peptolide substrate having the following amino acid sequences: R.sub.1 -Pro-Leu-Gly-Ile-Leu-Gly-Leu-R.sub.2, R.sub.1 -Gly-Pro-Leu-Gly-Ile-Leu-Gly-Ala-R.sub.2, R.sub.1 -Pro-Leu-Gly(O-Ile)-Leu-R.sub.2, R.sub.1 -Pro-Leu-Gly(O-Leu)-Leu-R.sub.2, and R.sub.1 -Pro-Leu-Gly(O-Leu)-Ala-R.sub.2, wherein R.sub.1 is H or N-protecting group, and R.sub.2 is terminal amide, carboxyl or ester group. |
Inventor(s): | Weingarten; Harold I. (University City, MO) |
Assignee: | Monsanto Company (St. Louis, MO) |
Application Number: | 06/485,762 |
Patent Claims: | see list of patent claims |
Details for Patent 4,425,428
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Try a Trial | 2002-04-08 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |