Last Updated: August 9, 2026

Patent: 10,906,986


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Summary for Patent: 10,906,986
Title:Prevention of disulfide bond reduction during recombinant production of polypeptides
Abstract:Provided herein are methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.
Inventor(s):Kao Yung-Hsiang, Laird Michael W., Schmidt Melody Trexler, Wong Rita L., Hewitt Daniel P.
Assignee:Genentech, Inc.
Application Number:US16847317
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

United States Patent 10,906,986 Claims and US Patent Landscape: Coverage, Likely Claim Scope, Expiration, and Generic Risk

What does US Patent 10,906,986 claim, and what is the likely technical scope?

US 10,906,986 is not analyzable from the information provided in this chat.

Why can’t the claim set for US 10,906,986 be reliably reconstructed here?

A claims-level patent landscape requires the actual patent specification and claim text (claim dependencies, claim numbering, defined terms, exemplified embodiments, and prosecution history signals). No such data is present in the provided input.

Which other US patents typically surround 10,906,986 in an estate?

Unable to provide a complete, accurate estate map for 10,906,986 without the patent family identifiers and document text.

When does US 10,906,986 expire and how does PTA/TL affect exclusivity?

Unable to determine expiration and enforceable term adjustments for 10,906,986 without filing/priority dates and prosecution history facts.

What patents block generic or Paragraph IV entry for the same drug or method?

Unable to identify blocking patents tied to 10,906,986 without knowing the covered active, dosage form, method-of-use, and corresponding Orange Book listings.

What Orange Book status applies to the subject matter of US 10,906,986?

Unable to map Orange Book status because the drug/active ingredient associated with 10,906,986 is not provided.

How strong is the patent estate behind US 10,906,986 for enforceability?

Unable to assess strength without claim language, independent claim limitations, prior art citations, and known litigation status.

What claim elements usually determine novelty and infringement risk in patents like 10,906,986?

No claim-specific elements are available to anchor this analysis.

How many US continuations or related filings are likely in the 10,906,986 family?

A family-size estimate requires bibliographic data and citations not included in the provided input.

Are there likely design-around or workaround pathways?

Workaround analysis requires the actual claim limitations (ranges, composition features, process steps, device/kit features, sequence constraints, and defined parameters) that are not available.

What patent litigation affects US 10,906,986?

Litigation requires a docket-level identifier, case captions, and asserted claims list, none of which are provided.

What is the commercial and regulatory exposure tied to US 10,906,986?

Exposure cannot be quantified without the covered product linkage (NDA/BLA), indication, FDA approvals, and current competitors.

Key Takeaways

  • US Patent 10,906,986 cannot be analyzed for claim scope or landscape coverage with accuracy using the information provided in this chat.
  • A valid claims-and-landscape assessment requires the patent’s claim text, family identifiers, priority/filing dates, and the associated drug/regulatory linkage.

FAQs

  1. What is the claim scope of US 10,906,986 in independent claims?
  2. What is the patent expiration date for US 10,906,986 including PTA?
  3. Which earlier patents or publications most likely anticipate US 10,906,986?
  4. Does US 10,906,986 align with Orange Book-listed exclusivities for a specific NDA?
  5. Which generic or biosimilar filings are at risk due to US 10,906,986?

References

No sources were provided in the prompt, and no patent document text or bibliographic data was supplied for US 10,906,986.

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Details for Patent 10,906,986

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 February 26, 2004 10,906,986 2040-04-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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