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Last Updated: April 26, 2024

Patent: 10,265,288

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Summary for Patent: 10,265,288

Title:	Methods and compositions for the treatment of proliferative disorders
Abstract:	The invention features methods of treating a proliferative disorder characterized by elevated Pin1 marker levels and/or reduced Pin1 Ser71 phosphorylation in a subject by administering a retinoic acid compound. Additionally, the invention features methods of treating proliferative disorders (e.g., proliferative disorders characterized by elevated Pin1 marker levels) by administering a retinoic acid compound in combination with another anti-proliferative compound. Finally, the invention also features methods including high-throughput screens for discovering and validating Pin1 inhibitors.
Inventor(s):	Lu; Kun Ping (Newton, MA), Wei; Shuo (Chestnut Hill, MA), Zhou; Xiao Zhen (Newton, MA)
Assignee:	Beth Israel Deaconess Medical Center, Inc. (Boston, MA)
Application Number:	14/334,052
Patent Claims:	see list of patent claims

Details for Patent 10,265,288

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Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	09/25/1998	⤷ Try a Trial	2031-03-14
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>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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