Patent: 9,932,388
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Summary for Patent: 9,932,388
Title: | Chromatographic process for producing high purity fibrinogen and thrombin |
Abstract: | The present invention relates to a chromatographic process for obtaining purified fibrinogen and thrombin from human plasma. The purified fibrinogen and thrombin preparations contain plasminogen in amounts less than 1 ug/mL. The low levels of plasminogen eliminates use of a proteolytic inhibitor, such as aprotinin in fibrin sealant kits which are used for human therapeutic applications. |
Inventor(s): | Nuvula; Ashok Kumar (Hyderabad, IN), Samaddar; Mitali (Hyderabad, IN), Vadde; Neelima (Hyderabad, IN), Chakraborty; Zinia (Hyderabad, IN), Duggineni; Swapna Sagar (Hyderabad, IN), Komath; Uma Devi (Hyderabad, IN) |
Assignee: | Hemarus Therapeutics Limited (Hyderabad, IN) |
Application Number: | 14/883,574 |
Patent Claims: | see list of patent claims |
Details for Patent 9,932,388
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bayer Healthcare Pharmaceuticals Inc. | TRASYLOL | aprotinin | Injection | 020304 | 12/29/1993 | ⤷ Try a Trial | 2034-11-13 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |