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Last Updated: March 30, 2023

Patent: 9,814,672


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Summary for Patent: 9,814,672
Title:Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi
Abstract: We disclose a composition comprising an echogenic liposome (ELIP) having an exterior surface, an interior surface, and at least one bilayer comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and a thrombolytic compound trapped by the ELIP. We also disclose a method of treating a medical condition in a patient characterized by a thrombus in the patient\'s vasculature, comprising administering to the patient the composition in an amount effective to reduce the size of the thrombus.
Inventor(s): Laing; Susan T. (Houston, TX), Huang; Shaoling (Houston, TX), McPherson; David D. (Houston, TX), Holland; Christy K. (Cincinnati, OH), Klegerman; Melvin E. (Houston, TX)
Assignee:
Application Number:12/044,189
Patent Claims:see list of patent claims

Details for Patent 9,814,672

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 12/22/1994 ⤷  Sign Up 2027-03-09
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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