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Last Updated: July 3, 2020

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Patent: 9,757,437

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Summary for Patent: 9,757,437
Title:Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
Abstract: Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.
Inventor(s): Blair; Henry (Boston, MA), Beck; Thomas (Concord, MA), Ladner; Robert Charles (Ijamsville, MD)
Assignee: Dyax Corp. (Burlington, MA)
Application Number:14/271,105
Patent Claims:see list of patent claims

Details for Patent 9,757,437

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Hlthcare TRASYLOL aprotinin INJECTABLE;INJECTION 020304 001 1994-02-07   Start Trial Dyax Corp. (Burlington, MA) 2024-09-27 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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