Patent: 9,579,367
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Summary for Patent: 9,579,367
Title: | C-terminally tethered amino acids and their fibrinolytic therapeutic uses |
Abstract: | The present disclosure provides a C-terminal tethered amino acid for modulating the thrombolytic, fibrinolytic and/or anticoagulant properties of a coagulation protein. The present disclosure also provides a coagulation protein having a catalytic site modified, either at the histidine or serine residue, with the C-terminal tethered amino acid as well as therapeutic applications of those modified coagulation proteins. |
Inventor(s): | Pryzdial; Ed (Vancouver, CA) |
Assignee: | Canadian Blood Services (Ottawa, CA) |
Application Number: | 14/303,101 |
Patent Claims: | see list of patent claims |
Details for Patent 9,579,367
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Microbix Biosystems Inc. | KINLYTIC | urokinase | For Injection | 021846 | 01/16/1978 | ⤷ Try a Trial | 2033-06-13 |
Genentech, Inc. | TNKASE | tenecteplase | For Injection | 103909 | 06/02/2000 | ⤷ Try a Trial | 2033-06-13 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |