Patent: 9,499,616

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Summary for Patent: 9,499,616

Title:	Modulated lysine variant species compositions and methods for producing and using the same
Abstract:	The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated lysine variant species compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNF.alpha. is detrimental, are also provided.
Inventor(s):	Subramanian; Kartik (Northborough, MA), Thiele; Mayda Perez (Vega Alta, PR), Zeng; Xiaobei (Carolina, PR), Wong; Chee Furng (Singapore, SG), Kaymakcalan; Zehra (Westborough, MA), Jing; Ying (Wellesley, MA), Chumsae; Christopher M. (North Andover, MA)
Assignee:	ABBVIE INC. (Chicago, IL)
Application Number:	14/923,966
Patent Claims:	see list of patent claims

Details for Patent 9,499,616

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2002-12-31	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2008-02-21	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2013-04-24	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2014-09-23	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2015-11-23	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2016-03-09	⤷ Free Forever Trial	2033-10-18
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	2016-10-17	⤷ Free Forever Trial	2033-10-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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