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Last Updated: November 27, 2021

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Patent: 9,273,031

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Summary for Patent: 9,273,031
Title:Combination therapy with MDM2 and EFGR inhibitors
Abstract: Provided is a method of treating a proliferative disease, condition, or disorder in a subject by administering a combination of an inhibitor of p53 and MDM2 binding and an EGFR inhibitor. Various embodiments of the disclosed methods provide a synergistic anti-proliferative or anti-apoptotic effect compared to administration of one agent alone.
Inventor(s): Errico; Joseph P. (Warren, NJ), Mugrage; Benjamin (Cranbury, NJ), Turchi; Ignatius (Yardley, PA), Sills; Matthew (Berkeley Heights, NJ), Ong; Jane (Franklin Park, NJ), Allocco; John (Staten Island, NY), Wines; Pam (Manalapan, NJ), Bastos; Margarita (Plainsboro, NJ)
Assignee: Errico; Joseph P. (Warren, NJ)
Application Number:14/571,770
Patent Claims:see list of patent claims

Details for Patent 9,273,031

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company ERBITUX cetuximab Injection 125084 2004-02-12 ⤷  Try it Free 2039-02-26
Eli Lilly And Company ERBITUX cetuximab Injection 125084 2007-03-28 ⤷  Try it Free 2039-02-26
Amgen, Inc. VECTIBIX panitumumab Injection 125147 2006-09-27 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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