Patent: 8,512,706
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Summary for Patent: 8,512,706
| Title: | Compositions of F(ab\').sub.2 antibody fragments |
| Abstract: | The present invention is directed to a pharmaceutical composition comprising F(ab\').sub.2 antibody fragments that are preferably free from albumin and of whole antibodies and also substantially free of pyrogens, and an effective amount of a pharmaceutically acceptable carrier. It is also directed to a method for the production of a pharmaceutical composition comprising F(ab\').sub.2 antibody fragments using scrum or blood plasma of a mammal that has been previously immunized as a source of antibodies. The serum or blood plasma is digested with an enzyme pepsin, followed by separation and purification until the pharmaceutical composition of F(ab\').sub.2 fragments is free of albumin and complete antibodies, and substantially free of pyrogens. |
| Inventor(s): | Lopez De Silanes; Juan (Mexico City, MX), Mancilla Nava; Rita Guadalupe (Mexico City, MX), Paniagua-Solis; Jorge F. (Mexico City, MX), Alagon Cano; Alejandro (Cuernavaca, MX), Garcia-Ubbelohde; Walter J. (Mexico City, MX) |
| Assignee: | Instituto Bioclon, S.A. DE C.V. (Mexico City, MX) |
| Application Number: | 13/298,778 |
| Patent Claims: | see list of patent claims |
Details for Patent 8,512,706
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Merck Sharp & Dohme Corp. | LACTRODECTUS MACTANS | antivenin (latrodectus mactans) | For Injection | 101062 | 02/13/1936 | ⤷ Try a Trial | 2021-03-05 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
