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Last Updated: October 1, 2020

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Patent: 8,226,949

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Summary for Patent: 8,226,949
Title:Stabilizing alkylglycoside compositions and methods thereof
Abstract: The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example parathyroid hormone (PTH) or PTH analogs, amylin, a monoclonal antibody, insulin, Peptide T or analog thereof, gastrin, gastrin releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof.
Inventor(s): Maggio; Edward T. (San Diego, CA)
Assignee: Aegis Therapeutics LLC (San Diego, CA)
Application Number:12/618,558
Patent Claims:see list of patent claims

Details for Patent 8,226,949

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Glaxosmithkline NUCALA mepolizumab INJECTABLE;SUBCUTANEOUS 761122 001 2019-06-06   Start Trial Aegis Therapeutics LLC (San Diego, CA) 2026-06-23 RX search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial Aegis Therapeutics LLC (San Diego, CA) 2026-06-23 RX search
Genentech Inc RITUXAN HYCELA rituximab; hyaluronidase (human recombinant) SOLUTION;SUBCUTANEOUS 761064 002 2017-06-22   Start Trial Aegis Therapeutics LLC (San Diego, CA) 2026-06-23 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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Express Scripts
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