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Last Updated: September 22, 2020

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Patent: 8,071,113

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Summary for Patent: 8,071,113
Title:Live, oral vaccine for protection against Shigella dysenteriae serotype 1
Abstract: The invention relates to Salmonella typhi Ty21a comprising core-linked Shigella dysenteriae serotype 1 O-specific polysaccharide (O-Ps) and DNA encoding O antigen biosynthesis, said DNA selected from the group consisting of: a) the DNA sequence set out in any one of SEQ ID NOs: 1 and 2 and species homologs thereof; b) DNA encoding Shigella dysenteriae serotype 1 polypeptides encoded by any one of SEQ ID NOs: 1 and 2, and species homologs thereof; and c) DNA encoding a O antigen biosynthesis gene product that hybridizes under moderately stringent conditions to the DNA of (a) or (b); and related sequences, compositions of matter, vaccines, methods of using, and methods of making.
Inventor(s): Kopecko; Dennis J. (Silver Spring, MD), Xu; DeQi (Columbia, MD)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC) N/A (N/A)
Application Number:11/597,301
Patent Claims:see list of patent claims

Details for Patent 8,071,113

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Paxvax Berna Gmbh VIVOTIF salmonella typhi ty21a CAPSULE, COATED 103123 1 1992-03-16   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) N/A (N/A) 2024-05-24 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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