Patent: 7,745,174
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Summary for Patent: 7,745,174
Title: | Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor |
Abstract: | The present invention relates to a hybrid Hepatocyte Growth Factor (HGF) gene which is prepared by inserting an inherent or foreign intron between exons 4 and 5 in HGF cDNA, which has a base sequence of SEQ ID NO: 2. The gene has high expression efficiency and simultaneously expresses two heterotypes of HGF and dHGF (deleted variant HGF). Further the gene may be used for treating or preventing ischemic or liver diseases. |
Inventor(s): | Kim; Jong-Mook (Seoul, KR), Hahn; Woong (Goyang, KR), Park; Eun-Jin (Seoul, KR) |
Assignee: | Viromed Co., Ltd. (Seoul, KR) |
Application Number: | 12/650,860 |
Patent Claims: | see list of patent claims |
Details for Patent 7,745,174
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | See Plans and Pricing | 2022-03-20 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | See Plans and Pricing | 2022-03-20 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | See Plans and Pricing | 2022-03-20 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |