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Generated: July 23, 2019

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Patent: 7,547,680

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Summary for Patent: 7,547,680
Title:Benzimidazole derivatives and medical uses thereof
Abstract: The present invention provides benzimidazole derivatives represented by the following formula (I) or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exert an inhibitory activity on sodium-dependent nucleoside transporter 2 and are useful for a disease associated with an abnormality of plasma uric acid level. The compounds of the present invention are useful for the prevention or treatment of gout, hyperuricemia, urinary lithiasis, hyperuricemic nephropathy or the like. In the formula, n is 1 or 2; R.sup.1 and R.sup.2 are H, a halogen atom, cyano group, optionally substituted alkyl group, optionally substituted aryl group or the like; R.sup.3 is H, a halogen atom, optionally substituted alkyl group or the like; R.sup.4 and R.sup.5 are H, a halogen atom, OH or the like; and R.sup.6 and R.sup.X are H or OH: R.sup.Y is F or OH. ##STR00001##
Inventor(s): Kikuchi; Norihiko (Nagano, JP), Nonaka; Yoshinori (Nagano, JP), Tatani; Kazuya (Nagano, JP), Hiratochi; Masahiro (Nagano, JP), Kuramochi; Yu (Nagano, JP), Isaji; Masayuki (Nagano, JP), Shimizu; Kazuo (Nagano, JP), Miyagi; Takashi (Nagano, JP)
Assignee: Kissei Pharmaceuticals, Co., Ltd. (Nagano, JP)
Application Number:11/473,957
Patent Claims:see list of patent claims

Details for Patent 7,547,680

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Sanofi Synthelabo ELITEK rasburicase VIAL; INTRAVENOUS 103946 001 2002-07-12 ➤ Sign Up Kissei Pharmaceuticals, Co., Ltd. (Nagano, JP) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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