Claims for Patent: 7,446,173

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Summary for Patent: 7,446,173

Title:	Polymer conjugates of interferon beta-1A and uses
Abstract:	An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the polyalkylene glycol moiety are arranged such that the interferon-beta-1a has an enhanced activity relative to another therapeutic form of interferon beta (interferon-beta-1b) and exhibits no decrease in activity as compared to non-conjugated interferon-beta-1a. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, e.g., diagnostic, applications.
Inventor(s):	Blake Pepinsky, Laura Runkel, Margot Brickelmaier, Adrian Whitty, Paula Hochman
Assignee:	Biogen MA Inc
Application Number:	US10/802,540

Details for Patent 7,446,173

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	March 07, 2002	7,446,173	2024-03-16
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	December 17, 2004	7,446,173	2024-03-16
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	December 21, 2012	7,446,173	2024-03-16
Biogen Inc.	PLEGRIDY	peginterferon beta-1a	Injection	125499	August 15, 2014	7,446,173	2024-03-16
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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