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Generated: September 15, 2019

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Patent: 7,445,775

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Summary for Patent: 7,445,775
Title:Yeast expression vector and a method of making a recombinant protein by expression in a yeast cell
Abstract: Vectors for the expression in yeast of mammalian plasminogen derivatives such as microplasminogen and miniplasminogen are presented. Methods for expression of these proteins in a methylotrophic yeast expression system are disclosed as well as the activation and stabilisation of the recombinant proteins. The proteins of this invention are used In the treatment of focal cerebral ischemic infarction and other thrombotic diseases.
Inventor(s): Collen; Desire Jose (London, GB), Nagai; Nubuo (Leuven, BE), Laroche; Yves (Brussel, BE)
Assignee: Thromb-X nv (Leuven, BE)
Application Number:10/450,976
Patent Claims:see list of patent claims

Details for Patent 7,445,775

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Thrombogenics, Inc JETREA ocriplasmin INJECTABLE; INTRAVITREAL 125422 001 2012-10-17 ➤ Sign Up Thromb-X nv (Leuven, BE) 2020-12-21 RX company
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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