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Last Updated: April 18, 2024

Patent: 7,445,775

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Summary for Patent: 7,445,775

Title:	Yeast expression vector and a method of making a recombinant protein by expression in a yeast cell
Abstract:	Vectors for the expression in yeast of mammalian plasminogen derivatives such as microplasminogen and miniplasminogen are presented. Methods for expression of these proteins in a methylotrophic yeast expression system are disclosed as well as the activation and stabilisation of the recombinant proteins. The proteins of this invention are used In the treatment of focal cerebral ischemic infarction and other thrombotic diseases.
Inventor(s):	Collen; Desire Jose (London, GB), Nagai; Nubuo (Leuven, BE), Laroche; Yves (Brussel, BE)
Assignee:	Thromb-X nv (Leuven, BE)
Application Number:	10/450,976
Patent Claims:	see list of patent claims

Details for Patent 7,445,775

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Thrombogenics Inc.	JETREA	ocriplasmin	Injection	125422	02/22/2017	⤷ Try a Trial	2020-12-21
Thrombogenics Inc.	JETREA	ocriplasmin	Injection	125422	10/17/2012	⤷ Try a Trial	2020-12-21
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,445,775

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Country	Patent Number	Estimated Expiration
Austria	378413	⤷ Try a Trial
Australia	1889002	⤷ Try a Trial
Cyprus	1107866	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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