Patent: 7,338,968
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Summary for Patent: 7,338,968
Title: | Thiadiazoles AS CXC- and CC- chemokine receptor ligands |
Abstract: | Disclosed are novel compounds of the formula: ##STR00001## and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and ischemia reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA. |
Inventor(s): | Biju; Purakkattle J. (Scotch Plains, NJ), Taveras; Arthur G. (Southborough, MA), Merritt; J. Robert (Ewing, NJ), Baldwin; John J. (Gwynedd Valley, PA), Yu; Younong (East Brunswick, NJ), Zheng; Junying (Bridgewater, NJ), Chao; Jianhua (Pompton Lakes, NJ), Aki; Cynthia J. (Livingston, NJ) |
Assignee: | Schering Corporation (Kenilworth, NJ) |
Application Number: | 11/013,753 |
Patent Claims: | see list of patent claims |
Details for Patent 7,338,968
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Genentech, Inc. | ACTIVASE | alteplase | For Injection | 103172 | 11/13/1987 | ⤷ Try a Trial | 2023-12-19 |
Genentech, Inc. | CATHFLO ACTIVASE | alteplase | For Injection | 103172 | 09/04/2001 | ⤷ Try a Trial | 2023-12-19 |
Janssen Biotech, Inc. | REOPRO | abciximab | Injection | 103575 | 12/22/1994 | ⤷ Try a Trial | 2023-12-19 |
Jubilant Hollisterstier Llc | N/A | positive skin test control-histamine | Injection | 103891 | 03/13/1924 | ⤷ Try a Trial | 2023-12-19 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |