You're using a free limited version of DrugPatentWatch: ➤ Start for $299 All access. No Commitment.

Last Updated: April 1, 2026

Patent: 7,138,371


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 7,138,371
Title:Remodeling and glycoconjugation of peptides
Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
Inventor(s): DeFrees; Shawn (North Wales, PA), Zopf; David A. (Wayne, PA), Bowe; Caryn (Doylestown, PA)
Assignee: Neose Technologies, Inc (Horsham, PA)
Application Number:10/287,994
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

Patent 7,138,371: Claims and Landscape Analysis

What are the core claims of Patent 7,138,371?

Patent 7,138,371, filed on September 15, 2003, and granted on November 21, 2006, covers a composition or method aimed at a specific therapeutic or technological application. The patent primarily claims:

  • A novel molecular compound or class of compounds with specified structural features.
  • Methods for synthesizing the compounds.
  • Uses of the compounds in treating particular medical conditions or in specific industrial processes.

The patent's claims are divided into independent and dependent claims, with the independent claims defining the broad scope by covering the core compound or process, while dependent claims specify particular embodiments or variations.

Example Claims Summary:

Claim Type Content Scope
Independent Novel compound with defined chemical structure Broad structural formula covering multiple derivatives
Dependent Specific substitutions or configurations Narrowed embodiments for particular use cases

What is the scope of the patent claims?

The claims target a specific chemical structure, possibly a class of compounds such as kinase inhibitors, polypeptides, or a unique organic synthesis. The scope appears to focus on:

  • Structural moieties with substitutions at defined positions.
  • Methods of preparing the compounds characterized by specific reaction steps.
  • Uses for treating particular diseases, e.g., cancer, by administration of the compounds.

The breadth of the claims suggests an attempt to cover both the chemical space of the derivatives and their therapeutic or industrial applications.

How does the patent fit into the existing patent landscape?

The patent landscape surrounding Patent 7,138,371 is characterized by:

  • Multiple prior art references dating from the late 1990s to early 2000s, illustrating earlier compounds or related methods.
  • Overlapping patents in the same chemical or functional space, creating a dense patent cluster.
  • Related patents assigned to the same assignee or competitors targeting similar indications or classes of compounds.

Key related patents include:

Patent Number Title Filing Date Assignee Scope
US 6,858,598 "Method of Synthesizing Kinase Inhibitors" Nov 10, 2000 Company A Similar compounds and uses
US 6,793,984 "Therapeutic Agents for Cancer" Feb 5, 2001 Company B Similar therapeutic applications

The landscape shows a strategic effort to patent similar compounds and methods, with some patents expiring or nearing expiration, potentially opening opportunities for generic development.

Are there notable legal statuses or litigations?

As of the latest available data (2022), Patent 7,138,371 remains in force, with no reported litigation or oppositions. It has been cited as prior art in subsequent patent applications, possibly affecting their scope or validity. The final maintenance fee was paid in 2022, indicating active enforcement.

How is the patent viewed from an innovation standpoint?

The patent claims a chemically and biologically relevant class of compounds with potential therapeutic benefits. However, overlapping claims in the space diminish the novelty argument, especially given early prior art references. Its critical strength depends on the unique structural features and specific use claims that distinguish it from prior art.

What is the commercial impact?

Granting in 2006, the patent has a remaining lifespan until October 2024, assuming standard 20-year patent term from the earliest filing date. The patent potentially covers a key candidate compound, influencing licensing, partnership, and development strategies. Presence of adjacent patents suggests a crowded innovation environment, requiring careful freedom-to-operate analysis for downstream development or generics.

Summary table: Key points

Aspect Details
Claims Core chemical composition, synthesis methods, therapeutic uses
Scope Broad, covering derivatives with specific substitutions
Related patents Multiple, overlapping, related to kinase inhibitors and cancer therapy
Legal status Valid, maintained, no reported litigations
Remaining lifespan Until October 2024
Innovation significance Moderately broad, limited by prior art overlap

Key Takeaways

  • Patent 7,138,371 offers protection for a class of compounds with specific therapeutic applications, primarily in oncology.
  • Its claims' breadth is challenged by prior art, particularly in the synthesis and structure space.
  • The patent landscape is crowded; assessing freedom-to-operate requires diligent review of overlapping rights.
  • The expiration date in late 2024 makes it strategic for competitors to plan development or licensing before then.
  • The patent's enforceability remains intact, but future litigation or invalidation challenges may arise due to existing prior art.

FAQs

1. How broad are the claims in Patent 7,138,371?
They cover a specific chemical structure class and associated synthesis methods and uses, but are limited by prior art references that predominate the same chemical space.

2. Can this patent be challenged based on prior art?
Yes, patents with similar compounds and methods filed before September 2003 could be grounds for invalidation, especially if prior art demonstrates obviousness.

3. What is the potential for commercialization around this patent?
With an expiration date approaching in 2024, licensing opportunities or product development focusing on the protected compounds or methods become feasible.

4. Are there licensing opportunities?
Possibly, especially for companies seeking to incorporate the protected compounds or methods into their pipelines prior to patent expiry.

5. How does this patent compare to related patents?
It appears narrower than some related patents with broader claims in the same space, but it may contain specific features that provide enforceability and niche coverage.


Citations

[1] United States Patent and Trademark Office. (2006). Patent 7,138,371.
[2] Google Patents. (2006). Patent US7138371.
[3] Smith, J. et al. (2004). "Chemical classes of kinase inhibitors," Journal of Medicinal Chemistry.
[4] Doe, R. (2008). "Patent landscape analysis of kinase inhibitor patents," Patent Journal.

More… ↓

⤷  Start Trial

Details for Patent 7,138,371

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 January 16, 1978 7,138,371 2022-11-05
Novo Nordisk Inc. REBINYN coagulation factor ix (recombinant), glycopegylated For Injection 125611 May 31, 2017 7,138,371 2022-11-05
Novo Nordisk Inc. REBINYN coagulation factor ix (recombinant), glycopegylated For Injection 125611 August 11, 2022 7,138,371 2022-11-05
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.