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Generated: September 22, 2019

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Patent: 6,858,409

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Summary for Patent: 6,858,409
Title: Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
Abstract:Compounds are disclosed having the general formula R.sub.1 --X--R.sub.2, wherein R.sub.1 and R.sub.2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R.sub.1 and R.sub.2 may be the same or different. Preferred R.sub.1 and R.sub.2 groups are interleukin-1 receptor antagonist, 30 kDa TNF inhibitor, interleukin-2 receptors and CR1 and muteins thereof. Also included are site selectively modified interleukin-1 receptor antagonist and 30 kDa TNF inhibitor.
Inventor(s): Thompson; Robert C. (Boulder, CO), Hannum; Charles H. (Sunnyvale, CA), Eisenberg; Stephen P. (Boulder, CO), Arend; William P. (Denver, CO), Joslin; Fenneke G. (Denver, CO), Sommer; Andreas (Danville, CA)
Assignee: Amgen Inc. (Thousand Oaks, CA) The Regents of the University of Colorado (Boulder, CO)
Application Number:08/482,283
Patent Claims:see list of patent claims

Details for Patent 6,858,409

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 001 2001-11-14   Try a Free Trial Amgen Inc. (Thousand Oaks, CA) The Regents of the University of Colorado (Boulder, CO) 2022-02-22 RX company
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 002 2001-11-14   Try a Free Trial Amgen Inc. (Thousand Oaks, CA) The Regents of the University of Colorado (Boulder, CO) 2022-02-22 RX company
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 003 2001-11-14   Try a Free Trial Amgen Inc. (Thousand Oaks, CA) The Regents of the University of Colorado (Boulder, CO) 2022-02-22 RX company
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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