Patent: 6,702,850

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Summary for Patent: 6,702,850

Title:	Multi-coated drug-eluting stent for antithrombosis and antirestenosis
Abstract:	A stent having a multi-layered coating adhered to its surface which can prevent restenosis and thrombosis at the implant site. The stent coating is comprised of two layers. The first layer is a polymeric coating with one or more biologically active agent(s) dispersed therein. The second layer is comprised of a hydrophobic heparinized polymer that inhibits blood coagulation and provides a hydrophilic surface for reducing the friction between stent and lesion site. In preferred embodiments of the invention, the multi-layered stent is effective in deterring restenosis and thrombosis at the implant site. In these same preferred embodiments, the multi-layered stent is capable of reducing the burst release of the biologically active agents from the first layer and sustaining a release of an effective amount of these agents for a relatively extended period of time. Methods of applying the multi-layered coating to the stent surface are also part of this invention.
Inventor(s):	Byun; Youngro (Seoul, KR), Yoon; Jung Han (Seoul, KR)
Assignee:	Mediplex Corporation Korea (Seoul, KR)
Application Number:	10/262,432
Patent Claims:	see list of patent claims

Details for Patent 6,702,850

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	01/10/1978	See Plans and Pricing	2039-02-26
Merck Teknika Llc	TICE BCG	bcg live	For Injection	102821	06/21/1989	See Plans and Pricing	2039-02-26
Clinigen, Inc.	PROLEUKIN	aldesleukin	For Injection	103293	05/05/1992	See Plans and Pricing	2039-02-26
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	02/20/1991	See Plans and Pricing	2039-02-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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