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Last Updated: March 29, 2023

Patent: 6,702,850

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Summary for Patent: 6,702,850
Title: Multi-coated drug-eluting stent for antithrombosis and antirestenosis
Abstract:A stent having a multi-layered coating adhered to its surface which can prevent restenosis and thrombosis at the implant site. The stent coating is comprised of two layers. The first layer is a polymeric coating with one or more biologically active agent(s) dispersed therein. The second layer is comprised of a hydrophobic heparinized polymer that inhibits blood coagulation and provides a hydrophilic surface for reducing the friction between stent and lesion site. In preferred embodiments of the invention, the multi-layered stent is effective in deterring restenosis and thrombosis at the implant site. In these same preferred embodiments, the multi-layered stent is capable of reducing the burst release of the biologically active agents from the first layer and sustaining a release of an effective amount of these agents for a relatively extended period of time. Methods of applying the multi-layered coating to the stent surface are also part of this invention.
Inventor(s): Byun; Youngro (Seoul, KR), Yoon; Jung Han (Seoul, KR)
Assignee: Mediplex Corporation Korea (Seoul, KR)
Application Number:10/262,432
Patent Claims:see list of patent claims

Details for Patent 6,702,850

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 01/10/1978 See Plans and Pricing 2039-02-26
Merck Teknika Llc TICE BCG bcg live For Injection 102821 06/21/1989 See Plans and Pricing 2039-02-26
Clinigen, Inc. PROLEUKIN aldesleukin For Injection 103293 05/05/1992 See Plans and Pricing 2039-02-26
Amgen, Inc. NEUPOGEN filgrastim Injection 103353 02/20/1991 See Plans and Pricing 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

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