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Generated: August 21, 2019

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Patent: 6,479,538

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Summary for Patent: 6,479,538
Title: Cyclic ether vitamin D3 compounds, 1.alpha.(OH)3-EPI-vitamin D3 compounds and uses thereof
Abstract:Novel cyclic ether vitamin D3 compounds having a cyclic ether side chain are disclosed. These compounds were first identified as metabolites of 3-epi vitamin D3 produced via a tissue-specific metabolic pathway which catalyzes the formation of a cyclic ether structure. Also disclosed are 1.alpha.(OH) 3-epi vitamin D3 compounds, which are produced via the epimerization of a 3-.beta.-hydroxyl group of 1.alpha.(OH) vitamin D3 precursor in vivo. The vitamin D3 compounds of the present invention can be used as substitutes for natural and synthetic vitamin D3 compounds.
Inventor(s): Reddy; Satayanarayana G. (Barrington, RI)
Assignee: Women and Infants Hospital (Providence, RI)
Application Number:09/617,881
Patent Claims:see list of patent claims

Details for Patent 6,479,538

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Try a Free Trial Women and Infants Hospital (Providence, RI) 2017-05-16 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Try a Free Trial Women and Infants Hospital (Providence, RI) 2017-05-16 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Try a Free Trial Women and Infants Hospital (Providence, RI) 2017-05-16 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Try a Free Trial Women and Infants Hospital (Providence, RI) 2017-05-16 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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International Patent Family for US Patent 6,479,538

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 9851678 Nov 19, 1998
United States of America 2003125309 Jul 03, 2003
United States of America 2008188548 Aug 07, 2008
United States of America 6100294 Aug 08, 2000
United States of America 6121312 Sep 19, 2000
Japan 2002505668 Feb 19, 2002
European Patent Office 0981523 Dec 07, 2005
>Country >Patent Number >Publication Date

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