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Last Updated: April 26, 2024

Patent: 6,462,041

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Summary for Patent: 6,462,041

Title:	Gambogic acid, analogs and derivatives as activators of caspases and inducers of apoptosis
Abstract:	The present invention is directed to gambogic acid, analogs and derivatives thereof, represented by the general Formulae I-III: ##STR1## wherein R.sub.1 -R.sub.5 are defined herein. The present invention also relates to the discovery that compounds having Formula I-III are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled cell growth and spread of abnormal cells occurs.
Inventor(s):	Cai; Sui Xiong (San Diego, CA), Zhang; Han-Zhong (San Diego, CA), Wang; Yan (San Diego, CA), Tseng; Ben (San Diego, CA), Kasibhatla; Shailaja (San Diego, CA), Drewe; John A. (Costa Mesa, CA)
Assignee:	Cytovia, Inc. (San Diego, CA)
Application Number:	09/495,120
Patent Claims:	see list of patent claims

Details for Patent 6,462,041

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>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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