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Last Updated: April 26, 2024

Patent: 5,824,784

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Summary for Patent: 5,824,784

Title:	N-terminally chemically modified protein compositions and methods
Abstract:	Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
Inventor(s):	Kinstler; Olaf B. (Thousand Oaks, CA), Gabriel; Nancy E. (Newbury Park, CA), Farrar; Christine E. (Newbury Park, CA), DePrince; Randolph B. (Raleigh, NC)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	08/321,510
Patent Claims:	see list of patent claims

Details for Patent 5,824,784

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen, Inc.	NEULASTA	pegfilgrastim	Injection	125031	01/31/2002	⤷ Try a Trial	2039-02-26
Amgen, Inc.	NEULASTA ONPRO	pegfilgrastim	Injection	125031	12/23/2014	⤷ Try a Trial	2039-02-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,824,784

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Country	Patent Number	Estimated Expiration
Austria	179991	⤷ Try a Trial
Austria	277078	⤷ Try a Trial
Australia	1841995	⤷ Try a Trial
Australia	706700	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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