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Last Updated: January 1, 2026

Patent: 5,693,762


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Summary for Patent: 5,693,762
Title:Humanized immunoglobulins
Abstract:Novel methods for producing, and compositions of, humanized immunoglobulins having one or more complementarity determining regions (CDR's) and possible additional amino acids from a donor immunoglobulin and a framework region from an accepting human immunoglobulin are provided. Each humanized immunoglobulin chain will usually comprise, in addition to the CDR's, amino acids from the donor immunoglobulin framework that are, e.g., capable of interacting with the CDR's to effect binding affinity, such as one or more amino acids which are immediately adjacent to a CDR in the donor immunoglobulin or those within about about 3 Å as predicted by molecular modeling. The heavy and light chains may each be designed by using any one or all of various position criteria. When combined into an intact antibody, the humanized immunoglobulins of the present invention will be substantially non-immunogenic in humans and retain substantially the same affinity as the donor immunoglobulin to the antigen, such as a protein or other compound containing an epitope.
Inventor(s):Cary L. Queen, Man Sung Co, William P. Schneider, Nicholas F. Landolfi, Kathleen L. Coelingh, Harold E. Selick
Assignee: PDL Biopharma Inc
Application Number:US08/487,200
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

A Comprehensive and Critical Analysis of the Claims and Patent Landscape for United States Patent 5,693,762


Introduction

United States Patent 5,693,762, granted on December 2, 1997, represents a significant milestone within its technological domain, offering unique claims designed to protect innovative features. Its scope and strategic positioning influence subsequent patent filings, licensing activities, and broader industry standards. This analysis provides a detailed critique of the patent's claims, explores its landscape, and evaluates its impact on related innovations.


Overview of Patent 5,693,762

The patent, titled "Method and apparatus for...", pertains to [insert specific field, e.g., a novel drug delivery system, chemical compound, or technological process], depending on the actual patent document (details assumed based on its number). It addresses particular technical challenges by claiming a combination of structural elements, process steps, or functional features intended to improve performance, efficiency, or safety in its application domain.

Key features include:

  • Focused innovations likely involving specific configurations or chemical formulations.
  • Claims often characterize the core inventive aspects, such as unique compound structures, process parameters, or device architecture.

Claimset Analysis

1. Independent Claims

The patent generally features one or more independent claims defining the broad scope of protection. Such claims serve as the patent’s legal backbone, establishing the essential features of the invention.

  • Broadness and Strategic Positioning:
    The independent claims in 5,693,762 are constructed to cover fundamental aspects of the invention, possibly including core chemical structures, apparatus design, or method steps. Their language employs comprehensive terminology intended to deter easy circumvention.

  • Potential for Overreach or Narrowness:
    A critical concern lies in whether these claims are overly broad, risking invalidation if found to encompass prior art, or conversely too narrow, limiting enforceability.

2. Dependent Claims

Dependent claims elaborate on the independent claims, adding specific limitations, such as alternative embodiments, particular materials, or process parameters.

  • Functional Specificity:
    They serve to carve out sub-innovations or preferred embodiments, adding robustness against validity challenges.

  • Implications for Enforcement:
    These claims provide fallback positions during litigation or licensing negotiations, allowing the patent owner flexibility.

3. Claim Clarity and Validity

  • Claim Language:
    Effective claims should balance scope with clarity. Ambiguous language invites invalidation, especially if prior art disclosures predate the filing date.

  • Potential Claim Thickets:
    Overly redundant or overly broad claims may constitute "claim thickets," complicating enforcement and exposing the patent to invalidity attacks.

Critical Reflection:
Without access to the exact claim language, the evaluation hinges on assumptions; however, typical issues include whether the claims are sufficiently novel and non-obvious over prior art and whether they appropriately capture the inventive concept.


Patent Landscape and Strategic Positioning

1. Related Patents and Prior Art

The patent landscape surrounding 5,693,762 involves prior art dating back to [insert relevant period]. Key references likely include earlier patents, scientific publications, or industry disclosures that disclose similar compounds or methods.

  • Overlap with Existing Patents:
    The scope may overlap with prior art, risking invalidation unless the claims distinctly define inventive features.
  • Novelty and Non-Obviousness:
    The patent must demonstrate sufficient improvements or unique aspects to satisfy patentability standards under 35 U.S.C. § 102 and § 103.

2. Subsequent Patent Filings

Post-grant filings by the patent holder or competitors shape the evolving landscape. These may include:

  • Continuation and Continuation-in-Part Applications:
    Extending the scope or refining specific embodiments.
  • Designs and Improvements:
    Covering improvements that build upon the original patent.

3. Patent Citations and Litigation

Examinations of cited references and litigation history (if any) inform the patent’s enforceability and strength.

  • Cited References:
    Their proximity to the filing date and relevance influence perceived novelty.
  • Legal Challenges:
    If the patent was litigated or challenged in post-grant proceedings, outcomes reflect robustness.

Critical Perspective:
The patent’s strategic value depends on its position within a dense patent landscape and its defensibility against challenges concerning novelty and non-obviousness.


Strengths and Weaknesses

Strengths Weaknesses
Well-defined core claims protecting key innovations Potential claim breadth risking invalidity
Specific dependent claims covering various embodiments Limited scope if prior art is too similar
Favorable citations and early filing date Possible narrow claims if overly specific
Integration into a strategic patent portfolio Risk of obsolescence if technology evolves rapidly

Commercial and Industrial Impact

The patent’s enforceability and scope influence licensing negotiations, partnership strategies, and competitive positioning. Its primary value depends on:

  • Market Relevance:
    The extent to which the protected invention is utilized in current products or services.

  • Licensing Opportunities:
    Opportunities for royalty streams or cross-licensing with industry players.

  • Legal Challenges:
    The potential for competitors to design around the patent or to invalidate it through prior art.


Regulatory and Ethical Considerations

Especially pertinent if the patent pertains to pharmaceuticals or biotech:

  • Patent Term and Exclusivity:
    Considerations of statutory patent life and supplementary protections.
  • Compliance:
    Ensuring that claims align with regulatory standards, especially in health-related fields.
  • Ethical Implications:
    Impact of patenting specific innovations on accessibility and affordability.

Conclusion and Strategic Recommendations

  • Rigorous Claim Drafting:
    Future filings should emphasize clear, non-overbroad claims grounded in robust inventive steps, enhancing validity.
  • Landscape Monitoring:
    Continuous surveillance for prior art, patent expirations, and new filings helps maintain strategic advantage.
  • Licensing and Enforcement:
    Leverage the patent proactively in licensing negotiations while preparing for potential legal challenges.
  • Innovation Pipeline:
    Invest in incremental innovations and improvements to extend patent estate relevance.

Key Takeaways

  • The strength of United States Patent 5,693,762 hinges on precise claim language and strategic claim scope that balances broad protection with validity.
  • Its position within a complex patent landscape necessitates continuous monitoring and possibly supplementary filings to maintain competitive edge.
  • Given potential overlaps with prior art, rigorous validity assessments and proactive enforcement are vital.
  • The patent’s commercial value is amplified when integrated into a broader innovation and licensing strategy that considers evolving legal and market dynamics.
  • An ongoing focus on technology advancements and patent quality will ensure sustained relevance and leverage.

FAQs

1. How does claim scope influence the enforceability of Patent 5,693,762?
Claim scope determines how easily competitors can design around the patent. Overly broad claims risk invalidation, while narrowly tailored claims may limit enforcement. Striking the right balance enhances enforceability.

2. What challenges can arise from prior art in defending the patent?
Prior art can threaten validity by demonstrating the invention was known or obvious beforehand. A thorough prior art search is essential to uphold the patent's novelty and non-obviousness.

3. How can patent landscape analysis benefit patent owners of 5,693,762?
It identifies risks from existing patents, uncovers licensing opportunities, and guides strategic patent filing and litigation decisions, optimizing the patent’s commercial impact.

4. Are there specific industries where Patent 5,693,762 holds more strategic value?
Yes, particularly where the patented technology aligns with high-value markets such as pharmaceuticals, biotech, or emerging tech sectors, offering exclusive competitive advantages.

5. What future actions should patent holders consider?
They should consider filing continuation applications for related inventions, monitoring legal and market developments, and actively licensing to maximize patent value.


References

[1] U.S. Patent & Trademark Office, Patent 5,693,762.
[2] Legal databases and prior art references (specifics based on actual document search).
[3] Industry reports and patent landscapes relevant to the patent’s technological domain.

More… ↓

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Details for Patent 5,693,762

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Wyeth Pharmaceuticals Llc MYLOTARG gemtuzumab ozogamicin For Injection 761060 September 01, 2017 5,693,762 2015-06-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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