Patent: 5,580,755

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Summary for Patent: 5,580,755

Title:	Human pluripotent granulocyte colony-stimulating factor
Abstract:	Disclosed are novel polypeptides possessing part or all of the primary structural conformation and one or more of the biological properties of a mammalian (e.g., human) pluripotent granulocyte colony-stimulating factor (\"hpG-CSF\") which are characterized in preferred forms by being the product of procaryotic or eucaryotic host expression of an exogenous DNA sequence. Sequences coding for part or all of the sequence of amino acid residues of hpG-CSF or for analogs thereof may be incorporated into autonomously replicating plasmid or viral vectors employed to transform or transfect suitable procaryotic or eucaryotic host cells such as bacteria, yeast or vertebrate cells in culture. Products of expression of the DNA sequences display, e.g., the physical and immunological properties and in vitro biological activities of isolates of hpG-CSF derived from natural sources. Disclosed also are chemically synthesized polypeptides sharing the biochemical and immunological properties of hpG-CSF.
Inventor(s):	Souza; Lawrence M. (Thousand Oaks, CA)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	08/459,298
Patent Claims:	see list of patent claims

Details for Patent 5,580,755

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	02/20/1991	See Plans and Pricing	2013-12-03
Amgen, Inc.	NEUPOGEN	filgrastim	Injection	103353	06/28/2000	See Plans and Pricing	2013-12-03
Amgen, Inc.	NEULASTA	pegfilgrastim	Injection	125031	01/31/2002	See Plans and Pricing	2013-12-03
Amgen, Inc.	NEULASTA ONPRO	pegfilgrastim	Injection	125031	12/23/2014	See Plans and Pricing	2013-12-03
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,580,755

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Country	Patent Number	Estimated Expiration
South Africa	866412	See Plans and Pricing
World Intellectual Property Organization (WIPO)	8701132	See Plans and Pricing
United States of America	6716606	See Plans and Pricing
United States of America	6379661	See Plans and Pricing
United States of America	6004548	See Plans and Pricing
>Country	>Patent Number	>Estimated Expiration

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