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Last Updated: June 9, 2023

Patent: 5,556,940

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Summary for Patent: 5,556,940
Title: Parathyroid hormone analogues for the treatment of osteoporosis
Abstract:Certain analogues of human parathyroid hormone (hPTH) have been found to be effective for the treatment of osteoporosis, while showing decreased side effects. Analogues showing this effect include all sequences from hPTH-(1-28)-NH.sub.2 to hPTH-(1-31)-NH.sub.2 and all sequences from [Leu.sup.27 ]-hPTH-(1-28)-NH.sub.2 to [Leu.sup.27 ]-hPTH-(1-33)-NH.sub.2. Also included are cyclic analogues cyclo(Lys.sup.26 -Asp.sup.30) [Leu.sup.27 ]-hPTH-(1-34)NH.sub.2 and cyclo (Lys.sup.27 -Asp.sup.30 )-hPTH-(1-34)-NH.sub.2. Analogues in the form of the carboxyl terminal amide are particularly effective.
Inventor(s): Willick; Gordon E. (Orleans, CA), Whitfield; James F. (Ottawa, CA), Surewicz; Witold (Orleans, CA), Sung; Wing L. (Gloucester, CA), Neugebauer; Witold (Ottawa, CA)
Assignee: National Research Council of Canada (Ottawa, CA)
Application Number:08/262,495
Patent Claims:see list of patent claims

Details for Patent 5,556,940

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 01/23/2015 ⤷  Try a Trial 2039-03-29
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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