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Generated: July 23, 2019

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Patent: 5,312,628

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Summary for Patent: 5,312,628
Title: Isolation of a soluble 42 KD pancreatic islet cell autoantigen
Abstract:A method of isolating soluble pancreatic islet antigen employs extraction with a non-ionic detergent and fractionation on a gel filtration column. Fractions are screened for high immunoreactivity with diabetic serum which is positive for ICA immunofluorescence when tested on tissue sections of a pancreas from a human blood group O donor. The isolated soluble antigen is suitable for measuring autoantibodies in both complement fixation assays as well as ELISA-type and immunoblotting formats. Methods of using isolated soluble antigen to test serum for autoantibodies are also taught.
Inventor(s): Cohen; Margo P. (New York, NY), Wu; Van-Yu (Cherry Hill, NJ)
Assignee: Exocell, Inc. (Philadelphia, PA)
Application Number:08/059,719
Patent Claims:see list of patent claims

Details for Patent 5,312,628

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up Exocell, Inc. (Philadelphia, PA) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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