Patent: 5,312,628

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Summary for Patent: 5,312,628

Title:	Isolation of a soluble 42 KD pancreatic islet cell autoantigen
Abstract:	A method of isolating soluble pancreatic islet antigen employs extraction with a non-ionic detergent and fractionation on a gel filtration column. Fractions are screened for high immunoreactivity with diabetic serum which is positive for ICA immunofluorescence when tested on tissue sections of a pancreas from a human blood group O donor. The isolated soluble antigen is suitable for measuring autoantibodies in both complement fixation assays as well as ELISA-type and immunoblotting formats. Methods of using isolated soluble antigen to test serum for autoantibodies are also taught.
Inventor(s):	Cohen; Margo P. (New York, NY), Wu; Van-Yu (Cherry Hill, NJ)
Assignee:	Exocell, Inc. (Philadelphia, PA)
Application Number:	08/059,719
Patent Claims:	see list of patent claims

Details for Patent 5,312,628

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	See Plans and Pricing	2011-05-17
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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