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Last Updated: March 29, 2023

Patent: 5,312,628

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Summary for Patent: 5,312,628
Title: Isolation of a soluble 42 KD pancreatic islet cell autoantigen
Abstract:A method of isolating soluble pancreatic islet antigen employs extraction with a non-ionic detergent and fractionation on a gel filtration column. Fractions are screened for high immunoreactivity with diabetic serum which is positive for ICA immunofluorescence when tested on tissue sections of a pancreas from a human blood group O donor. The isolated soluble antigen is suitable for measuring autoantibodies in both complement fixation assays as well as ELISA-type and immunoblotting formats. Methods of using isolated soluble antigen to test serum for autoantibodies are also taught.
Inventor(s): Cohen; Margo P. (New York, NY), Wu; Van-Yu (Cherry Hill, NJ)
Assignee: Exocell, Inc. (Philadelphia, PA)
Application Number:08/059,719
Patent Claims:see list of patent claims

Details for Patent 5,312,628

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 See Plans and Pricing 2011-05-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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