Patent: 4,729,957

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Summary for Patent: 4,729,957

Title:	Process for manufacture of L-asparaginase from erwinia chrysanthemi
Abstract:	A process for the recovery and purification of L-asparaginase from Erwinia chrysanthemi is disclosed. The process involves the preparation of cellular acetone powder extract followed by either an ion exchange and affinity chromatography purification steps or by affinity chromatography alone. The column eluent is then dialyzed to produce substantially pure L-asparaginase.
Inventor(s):	Lee; Shwu-Maan (Frederick, MD), Ross; John T. (Myersville, MD), Wroble; Marie H. (Mt. Airy, MD)
Assignee:	The United States of America as represented by the Department of Health (Washington, DC)
Application Number:	06/916,796
Patent Claims:	see list of patent claims

Details for Patent 4,729,957

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source
Merck	ELSPAR	asparaginase	VIAL	101063	001	1978-01-10	➤ Sign Up	The United States of America as represented by the Department of Health (Washington, DC)	➤ Sign Up	RX		search
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Patent Expiration	Status	Orphan	Source

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