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Patent: 4,729,957
Summary for Patent: 4,729,957
| Title: | Process for manufacture of L-asparaginase from erwinia chrysanthemi |
| Abstract: | A process for the recovery and purification of L-asparaginase from Erwinia chrysanthemi is disclosed. The process involves the preparation of cellular acetone powder extract followed by either an ion exchange and affinity chromatography purification steps or by affinity chromatography alone. The column eluent is then dialyzed to produce substantially pure L-asparaginase. |
| Inventor(s): | Lee; Shwu-Maan (Frederick, MD), Ross; John T. (Myersville, MD), Wroble; Marie H. (Mt. Airy, MD) |
| Assignee: | The United States of America as represented by the Department of Health (Washington, DC) |
| Application Number: | 06/916,796 |
| Patent Claims: | see list of patent claims |
Details for Patent 4,729,957
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck | ELSPAR | asparaginase | VIAL | 101063 | 001 | 1978-01-10 | Start Trial | The United States of America as represented by the Department of Health (Washington, DC) | 2005-03-08 | RX | search | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
