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Generated: July 19, 2019

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Patent: 4,729,957

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Summary for Patent: 4,729,957
Title: Process for manufacture of L-asparaginase from erwinia chrysanthemi
Abstract:A process for the recovery and purification of L-asparaginase from Erwinia chrysanthemi is disclosed. The process involves the preparation of cellular acetone powder extract followed by either an ion exchange and affinity chromatography purification steps or by affinity chromatography alone. The column eluent is then dialyzed to produce substantially pure L-asparaginase.
Inventor(s): Lee; Shwu-Maan (Frederick, MD), Ross; John T. (Myersville, MD), Wroble; Marie H. (Mt. Airy, MD)
Assignee: The United States of America as represented by the Department of Health (Washington, DC)
Application Number:06/916,796
Patent Claims:see list of patent claims

Details for Patent 4,729,957

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up The United States of America as represented by the Department of Health (Washington, DC) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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