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Last Updated: October 26, 2021

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Patent: 4,729,957

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Summary for Patent: 4,729,957
Title: Process for manufacture of L-asparaginase from erwinia chrysanthemi
Abstract:A process for the recovery and purification of L-asparaginase from Erwinia chrysanthemi is disclosed. The process involves the preparation of cellular acetone powder extract followed by either an ion exchange and affinity chromatography purification steps or by affinity chromatography alone. The column eluent is then dialyzed to produce substantially pure L-asparaginase.
Inventor(s): Lee; Shwu-Maan (Frederick, MD), Ross; John T. (Myersville, MD), Wroble; Marie H. (Mt. Airy, MD)
Assignee: The United States of America as represented by the Department of Health (Washington, DC)
Application Number:06/916,796
Patent Claims:see list of patent claims

Details for Patent 4,729,957

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Free Forever Trial 2005-03-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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