Last Updated: August 25, 2026

Patent: 12,311,015

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Summary for Patent: 12,311,015

Title:	Stable liquid thrombin compositions
Abstract:	The present invention provides methods for large scale preparation of sterile stable liquid thrombin composition comprised of glycerol; stable liquid thrombin compositions; and hemostatic composition and kits. The present invention further provides hemostatic compositions comprised of liquid thrombin, glycerol and gelatin. Further provided herein is a method for the large-scale production of a sterile liquid thrombin composition comprised of glycerol.
Inventor(s):	Erez Ilan, Omri Faingold, Sivan Doron
Assignee:	Omrix Biopharmaceuticals Ltd
Application Number:	US18/418,690
Patent Claims:	see list of patent claims

Details for Patent 12,311,015

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Omrix Biopharmaceuticals Ltd	EVITHROM	thrombin, topical (human)	Solution	125247	August 27, 2007	12,311,015	2044-01-22
Omrix Biopharmaceuticals Ltd	EVITHROM	thrombin, topical (human)	For Injection	125247	September 17, 2009	12,311,015	2044-01-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 12,311,015

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2020035848	⤷ Start Trial
United States of America	2024173388	⤷ Start Trial
United States of America	2020054720	⤷ Start Trial
United States of America	11911448	⤷ Start Trial
Mexico	2021001827	⤷ Start Trial
South Korea	20210046699	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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