Last Updated: November 9, 2026

Patent: 11,549,089

Summary for Patent: 11,549,089

Title:	Mechanical transfection devices and methods
Abstract:	A transfection device suitable for delivery of various macrostructures (e.g., mitochondria, bacteria, liposomes) is described and uses mechanical force to thereby induce active endocytosis in a target cell. Contemplated devices are able to achieve high throughput of transfected cells that remain viable and are capable of producing colonies.
Inventor(s):	Ting Wu
Assignee:	Nanocav LLC
Application Number:	US16/939,728
Patent Claims:	see list of patent claims

Details for Patent 11,549,089

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bluebird Bio Inc.	LYFGENIA	lovotibeglogene autotemcel	Suspension	125788	December 08, 2023	⤷ Start Trial	2040-07-27
Genetix Biotherapeutics Inc.	LYFGENIA	lovotibeglogene autotemcel	Suspension	125788	December 8, 2023	⤷ Start Trial	2040-07-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,549,089

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Country	Patent Number	Estimated Expiration
United States of America	10081816	⤷ Start Trial
United States of America	10760040	⤷ Start Trial
United States of America	11046976	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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