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Last Updated: December 16, 2025

Patent: 10,953,101


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Summary for Patent: 10,953,101
Title:Glycotargeting therapeutics
Abstract:Several embodiments of the present disclosure relate to therapeutic compositions configured to target the liver of a subject and that are useful in the treatment or prevention of one or more of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired. In several embodiments, the compositions are configured for clearance of a circulating protein or peptide or antibody associated with one or more of the above-mentioned maladies. Methods and uses of the compositions for induction of immune tolerance are also disclosed herein.
Inventor(s):Jeffrey A. Hubbell, David Scott Wilson
Assignee: Ecole Polytechnique Federale de Lausanne EPFL
Application Number:US15/925,628
Patent Claims:see list of patent claims

Details for Patent 10,953,101

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Biogen Inc. TYSABRI natalizumab Injection 125104 November 23, 2004 ⤷  Get Started Free 2038-03-19
Sanofi-aventis U.s. Llc ADLYXIN lixisenatide Injection 208471 July 27, 2016 ⤷  Get Started Free 2038-03-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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