Last Updated: September 24, 2026

Patent: 10,849,849

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Summary for Patent: 10,849,849

Title:	Subcutaneous HER2 antibody formulations
Abstract:	Fixed dose HER2 antibody formulations for subcutaneous administration are provided along with their use in the treatment of cancer. The formulations include fixed dose subcutaneous formulations of pertuzumab and subcutaneous co-formulations of pertuzumab and trastuzumab, and their use in the treatment of cancer.
Inventor(s):	Eng-Wong Jennifer, Kirschbrown Whitney, Khan Tarik, Lin Jasper, Alavattam Sreedhara, Garg Amit, Heeson Sarah, Badovinac-Crnjevic Tanja, Wurth Christine
Application Number:	US15872648
Patent Claims:	see list of patent claims

Details for Patent 10,849,849

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	5-May-04	⤷ Start Trial	2038-01-16
Bausch & Lomb Incorporated	VITRASE	hyaluronidase	Injection	021640	2-Dec-04	⤷ Start Trial	2038-01-16
Amphastar Pharmaceuticals, Inc.	AMPHADASE	hyaluronidase	Injection	021665	26-Oct-04	⤷ Start Trial	2038-01-16
Akorn, Inc.	HYDASE	hyaluronidase	Injection	021716	25-Oct-05	⤷ Start Trial	2038-01-16
Genentech, Inc.	PERJETA	pertuzumab	Injection	125409	8-Jun-12	⤷ Start Trial	2038-01-16
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,849,849

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Country	Patent Number	Estimated Expiration
Australia	2018210312	⤷ Start Trial
Australia	2020203066	⤷ Start Trial
Australia	2023210566	⤷ Start Trial
Canada	3047349	⤷ Start Trial
China	110167594	⤷ Start Trial
China	111714630	⤷ Start Trial
China	115089704	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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