Last Updated: July 13, 2026

Patent: 10,689,373

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Summary for Patent: 10,689,373

Title:	1,2-substituted cyclopentanes as orexin receptor antagonists
Abstract:	The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, ##STR00001## wherein L, X, R.sup.a, R.sup.b, R.sup.1, R.sup.2 and R.sup.3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
Inventor(s):	Fieldhouse; Charlotte (Cambridgeshire, GB), Glen; Angela (Cambridgeshire, GB), Maine; Stephanie (Cambridgeshire, GB), Fujimoto; Tatsuhiko (Kanagawa, JP), Robinson; John Stephen (Cambridgeshire, GB)
Assignee:	TAKEDA PHARMACEUTICAL COMPANY LIMITED (Osaka, JP)
Application Number:	15/995,586
Patent Claims:	see list of patent claims

Details for Patent 10,689,373

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Genentech, Inc.	ACTIVASE	alteplase	For Injection	103172	November 13, 1987	⤷ Start Trial	2038-06-01
Genentech, Inc.	CATHFLO ACTIVASE	alteplase	For Injection	103172	September 04, 2001	⤷ Start Trial	2038-06-01
Janssen Biotech, Inc.	REOPRO	abciximab	Injection	103575	December 22, 1994	⤷ Start Trial	2038-06-01
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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