Last Updated: June 30, 2026

Patent: 10,653,747

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Summary for Patent: 10,653,747

Title:	ApoE mimetic peptides and higher potency to clear plasma cholesterol
Abstract:	Disclosed are synthetic apolipoprotein E-mimicking peptides, derivatives thereof, and related peptides, which are useful as therapeutic agents for reducing plasma cholesterol; synthetic methods of making the peptides; pharmaceutical compositions comprising the peptides, and methods of treating lipid and metabolic disorders using the disclosed synthetic apolipoprotein E-mimicking peptides and compositions thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Inventor(s):	Gattadahalli M. Anantharamaiah, Dennis Goldberg
Assignee:	UAB Research Foundation , Anji Pharmaceuticals Inc
Application Number:	US15/329,735
Patent Claims:	see list of patent claims

Details for Patent 10,653,747

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Takeda Pharmaceuticals U.s.a., Inc.	ADYNOVATE	antihemophilic factor (recombinant), pegylated	For Injection	125566	November 13, 2015	⤷ Start Trial	2035-07-20
Takeda Pharmaceuticals U.s.a., Inc.	ADYNOVATE	antihemophilic factor (recombinant), pegylated	For Injection	125566	October 25, 2016	⤷ Start Trial	2035-07-20
Takeda Pharmaceuticals U.s.a., Inc.	ADYNOVATE	antihemophilic factor (recombinant), pegylated	For Injection	125566	March 13, 2017	⤷ Start Trial	2035-07-20
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,653,747

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Country	Patent Number	Estimated Expiration
Australia	2015298263	⤷ Start Trial
Brazil	112017001860	⤷ Start Trial
Canada	2954475	⤷ Start Trial
China	107074923	⤷ Start Trial
European Patent Office	3189069	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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