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Last Updated: December 28, 2025

Patent: 10,562,956

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Summary for Patent: 10,562,956

Title:	Recombinant fibrinogen
Abstract:	The present invention relates to nucleotide sequences encoding a fibrinogen alpha, beta or gamma chain. The sequences are optimized for expression in a eukaryotic cell culture system. Such optimized nucleotide sequences allow for the efficient expression of recombinant fibrinogen and variants thereof in intact form in a eukaryotic cell culture system.
Inventor(s):	Abraham Bout, Joseph Grimbergen, Jacob Koopman
Assignee:	Mallinckrodt Pharma IP Trading DAC
Application Number:	US15/331,942
Patent Claims:	see list of patent claims

Details for Patent 10,562,956

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Mallinckrodt Pharma Ip Trading Dac	RAPLIXA	fibrin sealant (human)	Powder	125523	April 30, 2015	⤷ Get Started Free	2036-10-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,562,956

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2010004004	⤷ Get Started Free
United States of America	2017037108	⤷ Get Started Free
United States of America	2011177524	⤷ Get Started Free
Poland	2310411	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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