Last Updated: November 8, 2026

Patent: 10,485,860

Summary for Patent: 10,485,860

Title:	Virulence factors of Streptococcus pnuemoniae
Abstract:	The present invention provides proteins/genes, which are essential for survival, and consequently, for virulence of Streptococcus pneumoniae in vivo, and thus are ideal vaccine candidates for a vaccine preparation against pneumococcal infection. Further, also antibodies against said protein(s) are included in the invention.
Inventor(s):	Hester Jeanette Bootsma, Pieter Jan Burghout, Peter Wilhelmus Maria Hermans, Johanna Jacoba Elisabeth Bijlsma, Oscar Paul Kuipers, Tomas Gerrit Kloosterman
Assignee:	Stichting Radboud Universitair Medisch Centrum
Application Number:	US15/354,102
Patent Claims:	see list of patent claims

Details for Patent 10,485,860

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	November 23, 2004	⤷ Start Trial	2036-11-17
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,485,860

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Country	Patent Number	Estimated Expiration
Canada	2683772	⤷ Start Trial
Denmark	2450054	⤷ Start Trial
European Patent Office	1980266	⤷ Start Trial
European Patent Office	2146743	⤷ Start Trial
European Patent Office	2251035	⤷ Start Trial
European Patent Office	2450054	⤷ Start Trial
European Patent Office	2460535	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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