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Last Updated: September 23, 2020

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Patent: 10,456,407

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Summary for Patent: 10,456,407
Title:Combination therapy for treating cancer
Abstract: The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents (such as tyrosine kinase inhibitors or VEGF/VEGFR inhibitors), particularly anticancer agents such as sunitinib, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
Inventor(s): Keilhack; Heike (Belmont, MA), Pili; Roberto (Indianapolis, IN)
Assignee: Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY)
Application Number:15/567,838
Patent Claims:see list of patent claims

Details for Patent 10,456,407

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Start Trial Epizyme, Inc. (Cambridge, MA) Health Research, Inc. (Buffalo, NY) 2035-04-20 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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